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  1. How psychedelics work, explained by Johns Hopkins professor Matthew Johnson.Subscribe to Big Think on YouTube https://www.youtube.com/channel/UCvQECJukTDE2...

    • 6 min
    • 825.5K
    • Big Think
  2. In this documentary, uncover how substances like LSD and magic mushrooms fueled a revolution in art, music, and societal norms.

    • 46 min
    • 12K
    • Absolute History
  3. We explore the history of human psychedelic usage, and also dive into the origin, properties, dangers, and benefits of the most popular psychedelics today: LSD, MDMA, Magic Mushrooms, DMT, and...

    • 180 min
    • 18.2K
    • Dan Cummins Presents: Bad Magic Productions
    • Set & Setting: priming for a mystical experience. The set and setting for a psychedelic experience is known to be a key determinant of outcomes, including of mystical experiences.
    • Drug dosage. The dosage of the psychedelic substance ingested is a key predictor of mystical experiences, with higher dosages more commonly associated with their occurrence.
    • Drug type. While all classical psychedelics can catalyse mystical experiences, much of the modern research has centred on psilocybin. However, some studies suggest that when administered in a supportive context, the psychedelic 5-MeO-DMT can elicit mystical experiences at higher rates than psilocybin did in research studies conducted by Johns Hopkins.
    • Absorption. Absorption is a personality trait that encompasses an individual’s propensity to become fully immersed or engaged in sensory and imaginative experiences.
  4. Psychedelic can be used to refer to what are called the 'classic psychedelic compounds': psilocybin, which is in magic mushrooms, LSD, DMT, which is in ayahuasca, mescaline, which is in...

    • Matthew W. Johnson
    • 2 min
  5. May 22, 2023 · Classic psychedelics seem to work by binding to the serotonin 2a receptor, one of the 15 specialized receptor molecules the serotonin system uses to coordinate brain activity. Entactogens and dissociative anesthetics don’t directly act on this receptor, which is why they “feel” different from hallucinogens.

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  7. Psychedelics: A neuroscientist's guide to how they change your brain - BBC Science Focus Magazine.

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