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3. When to start PEP (section 8): PEP should be initiated as soon as possible after exposure, preferably within 24 hours. PEP should not be initiated beyond 72 hours after exposure. 4. Baseline tests (section 9): All exposures: 1. Creatinine (and eGFR) 2. Alanine transaminase 3. HIV-1 Ag/Ab 4.
Aug 1, 2023 · Summary. Post-exposure prophylaxis for HIV must be initiated as soon as possible, ideally within 2 hours, and preferably within 24 hours of exposure. However, the period during which post-exposure prophylaxis (PEP) is most efficacious is often said to be within 72 hours of exposure. Most exposures have only a low risk of HIV transmission even ...
Jul 22, 2024 · PEP is most effective when initiated as soon as possible, ideally within 24 hours and no later than 72 hours after exposure. While a PEP regimen of two drugs can be effective, three drugs are preferred. It is recommended that people be given a 28-day prescription for PEP. This guideline includes recommended drug regimens for adults, adolescents ...
3. When to start PEP (Section 8) PEP should be initiated as soon as possible after expo-sure, preferably within 24 h. PEP should not be initiated beyond 72 h after exposure. 4. Baseline tests (Section 9) All exposures:
Abstract. We present the updated British Association for Sexual Health and HIV (BASHH) guidelines for post-exposure prophylaxis (PEP) to HIV following sexual exposures, occupational exposures and other nonoccupational exposures in the community. This serves as an update to the 2015 BASHH guideline on PEP following sexual exposures and the 2008 ...
- HIV Medicine
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Oct 3, 2024 · Request for PEP later than 72 hours after exposure: Because evidence indicates that PEP is ineffective when initiated more than 72 hours after exposure, clinicians should not initiate PEP after this time point Beymer, et al. 2017; Otten, et al. 2000; Smith, et al. 2000; Van Rompay, et al. 2000; Tsai, et al. 1998; Van Rompay, et al. 1998; Black 1997.
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NEW IN THE 2015 GUIDELINES: PEPSE is not routinely recommended after any type of sex with HIV-positive source. on antiretroviral therapy (ART) with a confirmed and sustained (>6 months) undetectable plasma HIV viral load (<200c/ml). Initiation of PEPSE is recommended as soon as possible after exposure, preferably.
