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Magic bullets. Following Louis Pasteur’s germ theory and Robert Koch’s work on identifying specific. bacteria, researchers began to find ways of killing germs inside the body without harming...
May 12, 2008 · By visualizing the differential affinities of chemical dyes for specific biological structures, Ehrlich taught us that, in the broadest sense, the biological effect of a chemical compound depends...
- Klaus Strebhardt, Axel Ullrich
- 2008
Paul Ehrlich decided to create magic bullets that behaved like antibodies using chemicals. Dyes Ehlrich argued that if certain dyes could stain bacteria, certain chemicals could also kill bacteria.
Ehrlich's discovery of Salvarsan in 1909 for the treatment of syphilis is termed as the first magic bullet. [7] This led to the foundation of the concept of chemotherapy. [8]
In it, Ehrlich presented the entire spectrum of known staining techniques and the chemistry of the pigments employed. While he was at the Charité, Ehrlich elaborated upon the differentiation of white blood cells according to their different granules.
The side-chain theory (German, Seitenkettentheorie) is a theory proposed by Paul Ehrlich (1854–1915) to explain the immune response in living cells. Ehrlich theorized from very early in his career that chemical structure could be used to explain why the immune response occurred in reaction to infection. He believed that toxins and antitoxins ...
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The Paul Ehrlich's Magic Bullet theory is fundamentally about targeted medical treatment. It signifies a therapeutic approach that aims to seek out and destroy diseased cells while leaving healthy cells unharmed. It effectively introduced the principle of selective toxicity.
