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Oct 20, 2015 · As a student, Ehrlich had already established the principles of modern hematology by describing distinct dye-staining properties of various leukocyte populations. 4-6 During his studies, he employed both alkaline and acid dyes but also invented new neutral dyes.
- Bernd Groner, Hans-Peter Horny, Fritz Sörgel, Udo Schumacher, Peter Valent
- 2015
Jan 10, 2014 · The basis of unique chemoreceptors being used to develop more specific agents that not only target particular pathogens but also have no toxic host effect was proposed by Ehrlich. He realized that moving from laboratory studies to clinical implementation was fraught with dangers.
- Glenn S Tillotson, Stephen H Zinner
- 2013
Jun 1, 2001 · Ehrlich's techniques of fixation and staining of blood films with aniline dyes greatly facilitated the study of blood and bone marrow. Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
Feb 5, 2016 · In the current article, we provide a short overview of Paul Ehrlich's life and career and a review of his major contributions to chemistry, hematology, immunology, pharmacology, drug development and translational medicine.
- Valent P
It is almost a century since Professor Paul Ehrlich of the Royal Institute for Experimental Therapy in Frankfurt (Germany) gave the address in Pathology on Chemotherapeutics: scientific prin-ciples, methods and results [1]. Many of the key points of Ehrlich’s treatise set the stage for modern therapeutics in the treatment of infectious diseases.
Sep 1, 2004 · Second, among the biologists of his days, Ehrlich was uniquely far-sighted in recognizing the role of chemistry for bringing accuracy to, and unifying concepts in, medicine.
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In a pioneering effort to detect drugs capable of spe-cifically killing certain microbes, Ehrlich synthesized a series of specific antimicrobial drugs, the most famous example being arsphenamine (Salvarsan ® ), the first syn-thetic agent against syphilis [5] .
