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Oct 20, 2015 · As a student, Ehrlich had already established the principles of modern hematology by describing distinct dye-staining properties of various leukocyte populations. 4-6 During his studies, he employed both alkaline and acid dyes but also invented new neutral dyes.
- Bernd Groner, Hans-Peter Horny, Fritz Sörgel, Udo Schumacher, Peter Valent
- 2015
Jun 1, 2001 · Ehrlich's techniques of fixation and staining of blood films with aniline dyes greatly facilitated the study of blood and bone marrow. Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
Jul 1, 2008 · Ehrlich described the side-chain theory of antibody formation and the mechanisms of how antibodies neutralize toxins and induce bacterial lysis with the help of complement and thus is...
- Stefan H E Kaufmann
- 2008
Ehrlich not only speculated on the behavior of synthetic chemicals toward his model of the protoplasm but also invoked biological specificity, a concept that would have a tremendous impact on immunology, drug development, and molecular biology. KEYWORDS - Paul Ehrlich; specificity; side chains; cellular structure; theory of immunity; chemotherapy.
Jan 10, 2014 · The basis of unique chemoreceptors being used to develop more specific agents that not only target particular pathogens but also have no toxic host effect was proposed by Ehrlich. He realized that moving from laboratory studies to clinical implementation was fraught with dangers.
- Glenn S Tillotson, Stephen H Zinner
- 2013
Dye and dyeing properties and theories were exploited for biological studies by the medical researcher Paul Ehrlich. Particular attention was paid to the side chains (functional or attached...
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Mar 11, 2004 · Ehrlich's prodigious talents in the laboratory — he was called a virtuoso of test tubes — were matched by a combination of intuition and deduction that marked him as a genius. He was the...