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  1. Aug 7, 2012 · Treatment with toceranib provided a statistically significant improvement in the objective response rate (ORR) versus placebo in the blinded phase. The ORR for all dogs receiving toceranib was 42.8% and the biological response rate including dogs with stable disease for more than 10 weeks was 59% (EBM I)3.

    • L. Blackwood, S. Murphy, P. Buracco, J. P. De Vos, P. De Fornel-Thibaud, J. Hirschberger, M. Kessler...
    • 2012
  2. Apr 5, 2024 · Abstract. Mast cell tumors (MCTs) are common cutaneous neoplasms in dogs. This article discusses recent updates in the management of mast cell disease, specifically the use of the MCT prognostic panel; evaluation of regional and sentinel lymph nodes for the presence of metastasis; and local and systemic treatments, including novel therapeutics such as tigilanol tiglate injection and gilvetmab.

  3. Jul 16, 2015 · Mast cell tumours (MCTs) are common tumours in dogs. They mainly affect the skin, although they can affect other tissues and organs. In recent years, there have been significant advances in predicting skin MCT behaviour and treatment, including the licensing of two tyrosine kinase inhibitors for the treatment of this condition.

  4. Aug 12, 2014 · Introduction. Mast cell tumors (MCTs) arise from malignantly transformed mast cells. In dogs, most of these tumors arise as primary tumors in the skin. They are the most common skin tumor in dogs, accounting for roughly 20% of all reported skin tumors. 1 Any breed may be affected with MCTs, but certain breeds are predisposed, including golden ...

    • Laura D Garrett
    • 10.2147/VMRR.S41005
    • 2014
    • Vet Med (Auckl). 2014; 5: 49-58.
  5. ” (SSDS) provides guidelines for evaluating superficial masses in dogs and cats. These guidelines will increase client awareness and will promote early cancer detection, diagnosis, and early surgical intervention. In veterinary medicine, most skin and subcutaneous tumors can be cured with surgery alone if diagnosed early when tumors are small.

  6. Moxidectin use (0.2–0.5 mg/kg PO Q 24 H) for treatment of canine demodicosis is supported by good evidence. 1,3,5,6. Moxidectin 2.5% + imidacloprid 10% (Advantage Multi, bayerdvm.com) is a spot-on medication approved for prevention of fleas, heartworm, and intestinal parasites in dogs of at least 7 weeks of age.

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  8. May 17, 2023 · Clinical findings and treatment of non-infectious meningoencephalomyelitis in dogs: a systematic review of 457 published cases from 1962 to 2008. The Veterinary Journal, 184, 290-297. Jeffery, N. and Granger, N. 2023: New insights into the treatment of meningoencephalomyelitis of unknown origin since 2009: A review of 671 cases.

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