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What is Hashimoto's thyroiditis? Hashimoto’s thyroiditis is an autoimmune disease (a disease involving the immune system) in which the body’s immune system attacks and destroys the thyroid gland (a small butterfly-shaped gland in the front of the neck).
- Diagnosis
How do doctors treat Hashimoto’s thyroiditis? Treatment...
- Diagnosis
Hashimoto's thyroiditis symptoms. The most obvious symptoms of Hashimoto’s thyroiditis in children and young people can be slow growth and gaining too much weight even though they are eating healthily.
What is pediatric thyroiditis (Hashimoto's disease)? Thyroiditis, also known as Hashimoto’s disease, is an autoimmune disorder - a disease in which the immune system attacks healthy organs or tissue (in this case, the thyroid). It is a major cause of hypothyroidism in children and adolescents.
Hashimoto thyroiditis is another name for the thyroid disorder autoimmune thyroiditis. This is an autoimmune condition in which the body’s immune system — which protects the body against infections — mistakenly attacks and causes inflammation in the thyroid gland.
- Epidemiology
- Diagnosis
- Clinical Presentation
- Pathology
- Radiographic Features
- Treatment and Prognosis
- History and Etymology
- Differential Diagnosis
- Practical Points
Hashimoto thyroiditis affects ~2% of all women (F:M = 10-15:1), most commonly in the 30-50 year range 17,22. 1. Turner syndrome 2. primary thyroid lymphoma 6 3. Hashimoto encephalopathy(rare) 4. Down syndrome 5. other autoimmune disorders 5.1. systemic lupus erythematosus (SLE) 5.2. type 1 diabetes mellitus 5.3. rheumatoid arthritis 5.4. Sjogren sy...
The diagnosis of Hashimoto's thyroiditis is usually based on the combination of clinical features, serology results, and ultrasound findings 17,22. However, cytology/histology remains the gold standard for diagnosis 22.
The clinical presentation is variable and some may be asymptomatic 17,22. Patients can present with a painless goiter +/- symptoms of hypothyroidism 17,22. There is often a gradual painless enlargement of the thyroid gland during the initial phase with atrophy and fibrosis later on in the course. Very rarely, patients can present with a painful thy...
There is autoimmunity to the thyroid glandwhich bears both humoral- and cell-mediated features. This is followed by lymphocytic infiltration of the thyroid gland with lymphoid follicles replacing thyroid follicles. This may affect the thyroid gland in either a diffuse or focal manner. Cell populations include: 1. lymphocytic aggregates 2. transform...
Ultrasound features can be variable depending on the severity and phase of disease as well as differentiate diffuse from nodular Hashimoto thyroiditis. Prominent reactive cervical nodes may be present, especially in level VI, but they have normal morphologic features ref. 1. typically an enlarged thyroid gland with a hypoechoic, diffusely heterogen...
Life-long oral administration of L-thyroxine (T4) is often required ref. 1. association with increased risk of the following thyroid cancers 21 1.1. papillary thyroid cancer (1.7x increased risk) 21 1.2. medullary thyroid cancer (2.7x increased risk) 21 1.3. thyroid lymphoma (13x increase risk) 6,21 2. myxedema coma due severe hypothyroidism (rare)...
It was first described in 1912 by Hakaru Hashimoto (1881-1934), a Japanese physician 7,while working in Germany. In his original description, he called it "struma lymphomatosa" 13.
For ultrasound appearances consider: 1. individual nodules in nodular Hashiomoto thyroiditis have overlapping imaging appearances with papillary thyroid carcinoma 17,18 2. subacute granulomatous (de Quervain) thyroiditis 3. thyroid lymphoma(rare)
patients are at higher risk for papillary thyroid carcinoma, so a discrete nodule should be considered for biopsy
Hashimoto’s Thyroiditis (hah-she-MOH-toes thyroy-DIE-tuss) is the common name for autoimmune hypothyroidism. It is one of the most common causes of hypothyroidism in school age children and can result in an underactive thyroid gland.
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Information. Living with thyroid disorders. Hashimoto's thyroiditis FAQs. How will I know if my child is on the right dose of levothyroxine? Your child’s symptoms should diminish within three to six months of starting to take levothyroxine.
