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The Code Breaker is an account of the science of genetic editing, beginning with the discovery of the concepts of evolution and heredity. It primarily focuses on Jennifer Doudna, who received the 2020 Nobel Prize in Chemistry along with French microbiologist Emmanuelle Charpentier for their work on the gene-editing tool CRISPR.
Mar 9, 2021 · In The Code Breaker, Walter Isaacson explains how the potential for using CRISPR and CaS9 to edit DNA was a significant advancement in gene editing with implications for the future of medicine and humanity. However, no ...
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- Walter Isaacson’s Perspective
- Introduction
- Storyshot #1: The Double Helix Changed Jennifer Doudna’s Life
- Storyshot #3: Crispr’S Discovery Was The Result of International Team Work
- Storyshot #4: Biotech Revolution Is The Future
- Storyshot #5: There’S A Patent War Over CRISPR
- Storyshot #6: Ethical Dilemmas Over CRISPR Should Be Taken Seriously
- Storyshot #7: CRISPR Can Create Issues of Selectivity and Inequality
- Storyshot #8: The World Is Using CRISPR to Tackle Covid-19
- Storyshot #9: We Need to Be Able to Reverse CRISPR
Walter Isaacsonis a historian, journalist, and proclaimed biographer. He is currently a Professor of History at Tulane and an advisory partner at Perella Weinberg Partners, a financial advisory firm. His former positions include CEO of the Aspen Institute, chairman of CNN and TIME magazine editor. In literature circles, Isaacson is well-known for h...
The Code Breakeris a fascinating ode to scientists who made remarkable discoveries about our genome. It focuses on Jennifer Doudna, who received the 2020 Nobel Prize in Chemistry, and her colleague, microbiologist Emmanuelle Charpentier. Although the Nobel-prize-winning gene-editing pioneer is the central figure of this publication, Isaacson offers...
The first quarter of The Code Breaker provides a brief biography of Jennifer Doudna. As a child, she found her aspiration in learning and education. When she was in sixth grade, she understood that she wanted to connect her life with chemistry and genetics. One day, she came home from school and found a book called “The Double Helix” by James Watso...
The author’s focus on Doudna’s contribution to CRISPR’s discovery gives the story a slight American bias. At the same time, the Nobel Prize Laureate herself emphasizes the importance of teamwork. Her international team consists of people from all over Europe, and the similarities they share (cultural, for instance) helped boost the group’s synergy....
Isaacson points out that he has written biographies on some of the most influential individuals within the tech sphere, like Steve Jobs. Computer technology has been the most influential sector over the last three or four decades. That said, the author believes the future is biotechnology. Instead of merely coding microchips, it will be possible to...
Doudna and her team are not unique in finding genome editing solutions. Competitive laboratories also have a lot to offer. While competition is the mother of progress, it has caused a significant patent battle. Jennifer Doudna and her teammates from the University of California, Berkeley, are in the red corner of the patent boxing match. Feng Zhang...
Tweaking our genome opens up endless prospects to improve human health and well-being. Wouldn’t we seize the opportunity if we could cure schizophrenia or AIDS by simply changing a few things in our code? Technology based on bacteria peculiarities has prospects for medical applications in more than 20 areas. It possesses the potential to cure cance...
The book raises many other ethical and moral issues. If we can heal humanity, where do we start? CRISPR technology in practice costs one million dollars, or even more. Does this mean that only the rich will benefit from it? How can we decide who will get their treatment and who will be forced to continue living with their disease? After all, if we ...
CRISPR could become our primary weapon in the fight against the most pressing issue at the time of this writing, i.e., the COVID-19 pandemic. Isaacson took the time to explain how the virus works and how it spread to pandemic proportions. Labs have worked on the cutting-edge mRNA vaccine, built upon tweaking the genes of the COVID-19 virus. Many pe...
Scientists like Doudner are in the process of developing ways to tackle CRISPR if things go wrong. Although this technology has tremendous potential, we are still unaware of how changing genetic code in one way will impact other genetic variables. We can’t turn a blind eye to the fact that some individuals may use CRISPR technology for evil. This i...
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- 17 min
Jun 15, 2023 · 1-Sentence-Summary: The Code Breaker details the life of Nobel Prize winner Jennifer Doudna, who embarked on — and successfully completed — a journey to invent a tool that allows us to edit the human genetic code and thus will change our lives, health, and future generations forever.
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- Socialbee
- Female
Chapter 1: Hilo. Watson’s Double Helix memoir inspires Doudna; Isaacson covers Darwin, Mendel, Crick and Watson (and Rosaland Franklin), and beyond. Chemical molecules determine what biological role it can play; chemistry becomes biology as atoms bond to create molecules. Chapter 2: The Gene.
- Gary Giroux
Isaacson says that after Doudna cracked the gene-editing code, she had a nightmare in which Adolf Hitler expressed interest in using her technology. Doudna realized it wasn’t enough to create powerful
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The Code Breaker by Walter Isaacson delves into the life and work of Jennifer Doudna, the pioneering scientist behind CRISPR gene-editing technology. It explores the ethical implications and potential of this revolutionary discovery.
