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Mar 2, 2021 · What is capsaicin treatment? Capsaicin is a substance that is derived from red-hot chilli peppers. It is available as a cream in two different strengths – 0.075% and 0.025%. The stronger cream, also called Axsain, is licensed for use in: Post-herpetic neuralgia. This is occurs when the varicella zoster virus – the virus that causes ...
- Overview
- Common uses
- Side effects of capsaicin cream
- Benefits of use
- Forms of capsaicin
- How to use capsaicin cream
- The takeaway
In addition to being a popular ingredient in spicy dishes worldwide, the chili pepper also has a surprising role in the medical world.
Capsaicin is the compound found in peppers that gives them their infamous hot and spicy kick. This compound is well-known for its pain-relieving properties. It works by affecting the neurotransmitter that communicates pain signals to the brain. In this way, it can reduce the perception of pain.
Arthritis
In arthritis, dysfunction of the pain receptors causes the body to experience prolonged symptoms of pain. Capsaicin cream is effective for reducing pain caused by various types of arthritis, including: •rheumatoid arthritis •osteoarthritis •fibromyalgia
Diabetic neuropathy
Diabetic neuropathy is nerve damage caused by diabetes. This condition affects about 50 percent of people with diabetes. The most common symptoms include the following, especially in feet and hands: •tingling or numbness •pain •weakness Topical analgesics, such as capsaicin cream, are common treatment options for this condition.
Migraine
Capsaicin cream is also used as a possible treatment option for migraine, a condition characterized by extremely painful headaches and neurological symptoms. The Migraine Research Foundation cites migraine as the third most common illness worldwide.
Although capsaicin is generally regarded as safe, there are some potential side effects of topical use. These side effects generally occur at the application site and most commonly include:
•burning
•itching
•redness
•swelling
•pain
Capsaicin cream is most often effective as an additional treatment for conditions that include pain. When used correctly and consistently, studies have shown that it may help to reduce the chronic pain caused by conditions such as arthritis, diabetes, and even migraines.
In one review, the researchers looked at the literature on capsaicin gel for hand and knee osteoarthritis. They found that in five trials, daily administration of capsaicin gel was significantly more effective for pain reduction than placebo. In the study that spanned over a period of 12-weeks, there was over a 50 percent reduction in pain with capsaicin gel use.
In a clinical study from 2014, researchers investigated the use of Qutenza, a topical 8 percent capsaicin patch, for peripheral neuropathic pain. The study participants were given a one-time treatment of up to 4 patches and monitored for a period of 12-weeks.
Results of the study indicated that even a single treatment was able to significantly reduce pain and improve quality of life.
Another 12-week study examined the use of clonidine gel and capsaicin cream for people with diabetic peripheral neuropathy (DPN). Study participants were asked to administer either cream topically three times a day for a period of 12 weeks.
The results indicated that both the clonidine gel and capsaicin cream were effective for significantly reducing DPN-associated pain. However, it should also be noted that over 58 percent of people in the capsaicin cream group experienced side effects. These included itchiness, red skin, and blisters.
There are many different types of capsaicin cream formulations that are available over the counter (OTC). The most common OTC preparations include:
•Capzasin-P – a capsaicin 0.1 percent topical analgesic cream
•Zostrix – a capsaicin 0.033 percent topical analgesic cream
•Zostrix Maximum Strength – a capsaicin 0.075 percent topical analgesic cream
Many pharmacies also carry their own brand versions of capsaicin creams.
OTC capsaicin creams vary in the percentage of capsaicin that’s used. Most preparations contain anywhere from 0.025 percent to 0.1 percent. The strongest formulation available OTC is 0.1 percent, which can be found in products labeled “high potency.”
Capsaicin cream is most commonly applied to the painful or affected area three to four times per day, depending on the condition:
•For rheumatoid arthritis and osteoarthritis, apply the cream to the most painful joints three times per day.
•For diabetic neuropathy, depending on the location of the neuropathy, apply the cream below the ankles or above the wrists, three to four times per day.
•For migraine or headache, apply the cream to the scalp area, being sure to avoid your eyes, three times per day.
OTC forms will include specific directions on the back of the package. Read these thoroughly before applying. When using the cream, be sure to rub the medicine into your skin until it’s fully absorbed.
Capsaicin cream should never be applied to open wounds or cuts. Once you apply the medication, it’s important to wash your hands as it can burn sensitive areas such as the eyes or mouth.
Research suggests that capsaicin cream can be an effective topical treatment option for people with certain painful conditions. There are several OTC options for capsaicin cream, many of which can be found at your local pharmacy or drugstore.
Speak with your healthcare professional about how you can incorporate capsaicin cream into your treatment.
Capsaicin 0.075% cream (Axsain ®) is licensed for the symptomatic relief of postherpetic neuralgia after open skin lesions have healed, and for the symptomatic relief of painful diabetic neuropathy (only under the direct supervision of a hospital consultant who has access to specialist resources) [ABPI, 2019b].
Jun 3, 2023 · Studies show capsaicin creams and patches can help relieve pain that's due to: Joint conditions like rheumatoid arthritis and osteoarthritis. Fibromyalgia. Muscle sprains and strains. Migraines...
The benefit of capsaicin cream is that it can temporarily reduce pain and, if used regularly, can provide prolonged pain relief. The recommendation for using capsaicin cream is at least 1-2 continuous weeks to see how well it works for you.
Capsaicin topical is used for temporary relief of muscle or joint pain caused by strains, sprains, arthritis, bruising, or backaches. Capsaicin topical is also used to treat nerve pain (neuralgia) in people who have had herpes zoster, or " shingles."
With topical use: Wash hands immediately after use (or wash hands 30 minutes after application if hands treated). With transdermal use: Nitrile gloves to be worn while handling patches and cleaning treatment areas (latex gloves do not provide adequate protection).
