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  1. May 16, 2018 · The aim of this review is to provide an overview of published values for the LQ parameters of human tumours as a guideline for radiation oncologists and radiation researchers to select appropriate radiobiological parameter values for LQ modelling in clinical radiotherapy.

    • C. M. van Leeuwen, A. L. Oei, J. Crezee, A. Bel, N. A. P. Franken, L. J. A. Stalpers, H. P. Kok
    • 2018
  2. Jan 1, 2018 · The targeted radiotherapy, with alpha- or beta-emitters, compared with external beam radiation therapy, offers the theoretical advantage to confine the delivered dose to the tumor and its immediate surrounding area and makes particularly sense for the radiotherapy of micrometastatic disease, minimal residual disease (MRD), or small volume ...

    • F. Lacoeuille, N. Arlicot, A. Faivre-Chauvet
    • 2018
  3. Jul 29, 2020 · Radiopharmaceutical therapy (RPT) is defined by the delivery of radioactive atoms to tumour-associated targets. RPT is a novel therapeutic modality for the treatment of cancer, providing...

    • George Sgouros, Lisa Bodei, Michael R. McDevitt, Jessie R. Nedrow
    • 2020
  4. Targeted alpha-particle therapy (or TAT) is an in-development method of targeted radionuclide therapy of various cancers. It employs radioactive substances which undergo alpha decay to treat diseased tissue at close proximity. [1] It has the potential to provide highly targeted treatment, especially to microscopic tumour cells.

  5. Mar 22, 2018 · Targeted alpha therapy combines the affinity and specificity of molecular targeting with potent, cytotoxic alpha particle emissions to deliver systemic, high-energy radiation selectively to cancer cells and the tumor microenvironment to control cancer.

    • Christopher Parker, Valerie Lewington, Neal Shore, Clemens Kratochwil, Moshe Levy, Ola Lindén, Walte...
    • 2018
  6. Aug 22, 2023 · Alpha emitters are radionuclides with good pharmacological characteristics for the treatment of cancer because they decay by emitting high linear energy transfer particles.

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  8. May 9, 2020 · Radionuclide therapy delivers cytotoxic radiation through energetic particles (alfa, beta, and auger) labeled to a carrier that specifically targets cancer cells. Targeted Alpha Therapy (TAT) employing alpha particle emitters is such a new approach to cancer treatment.

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