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- The mammalian ABL1 gene encodes the ubiquitously expressed nonreceptor tyrosine kinase ABL. In response to growth factors, cytokines, cell adhesion, DNA damage, oxidative stress, and other signals, ABL is activated to stimulate cell proliferation or differentiation, survival or death, retraction, or migration.
pubmed.ncbi.nlm.nih.gov/24421390/
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Jul 31, 2023 · Abetalipoproteinemia (ABL) is a rare autosomal recessive disorder marked by low or absent levels of plasma cholesterol, low-density lipoproteins (LDLs), and very-low-density lipoproteins (VLDLs). It should not be confused with a deficiency in beta-lipoproteins.
- Syeda Zeenat S. Junaid, Krunal Patel
- 2023/07/31
Jan 1, 2016 · Abl kinases can be activated by multiple stimuli leading to cytoskeletal reorganization required for cell morphogenesis, motility, adhesion and polarity. Depending on the cellular context, Abl kinases regulate cell survival and proliferation. Emerging data support important roles for Abl kinases in pathologies linked to inflammation.
- Aaditya Khatri, Jun Wang, Ann Marie Pendergast
- 10.1242/jcs.175521
- 2016
- J Cell Sci. 2016 Jan 1; 129(1): 9-16.
In response to growth factors, cytokines, cell adhesion, DNA damage, oxidative stress, and other signals, ABL is activated to stimulate cell proliferation or differentiation, survival or death, retraction, or migration.
- Jean Y. J. Wang
- 2014
The BCR-ABL test stands as a pivotal tool in the diagnosis and management of chronic myeloid leukemia. Its ability to pinpoint the presence of the BCR-ABL fusion gene offers insights into disease progression, guiding tailored treatment plans and fostering better patient outcomes.
There are 4 main blood groups defined by the ABO system: blood group A – has A antigens on the red blood cells with anti-B antibodies in the plasma. blood group B – has B antigens with anti-A antibodies in the plasma. blood group O – has no antigens, but both anti-A and anti-B antibodies in the plasma.
Learning Objectives. By the end of this section, you will be able to: Identify the most powerful buffer system in the body. Identify the most rapid buffer system in the body. Describe the protein buffer systems. Explain the way in which the respiratory system affects blood pH. Describe how the kidney affects acid-base balance.
How Blood Type Is Determined And Why You Need To Know. Blood types are determined by the presence or absence of certain antigens – substances that can trigger an immune response if they are foreign to the body.
