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  1. What your cervical screening results mean. Your cervical screening results letter will explain if human papillomavirus (HPV) was found in your sample, what your result means, and what happens next. Sometimes you'll be asked to come back in 3 months to have the test again.

    • Flowchart Part 1: Sample Taking and HPV Testing and Cytology Triage
    • Flowchart Part 2: Colposcopy
    • Flowchart Part 3: Abnormal Colposcopy Result Management

    1. Send out the invitation. Does the woman opt out of screening?

    Yes: The Cervical Screening Call and Recall Service (CSAS) is notified and the woman is ceased from screening. End of screening test pathway. No: Woman attends screening. Go to question 2.

    2. Carry out the test. Is the result high risk human papillomavirus (hrHPV) negative or positive?

    hrHPVnegative: return individual to routine recall. End of screening test pathway. hrHPVpositive: carry out cervical cytology test. Go to question 3. Note: If a test result is unavailable or cervical cytology is inadequate at any stage in the screening pathway, the sample must be repeated in no less than 3 months. Allow up to 2 consecutive unavailable or inadequate repeats – always refer to colposcopy at the second.

    3. Is cytology negative or abnormal?

    Cytology negative: screen again in 12 months’ time. Go to question 4. Cytology abnormal: refer to colposcopy. End of screening test pathway.

    1. Carry out the colposcopy examination. Is the examination adequate?

    Yes: go to question 3. No: go to question 2.

    2. What were the results of the hrHPV and cytology tests (leading to colposcopy referral)?

    hrHPV positive, cytology low grade or less (excluding borderline change in endocervical cells): repeat colposcopy in 12 months. If repeat colposcopy examination has inadequate outcome, consider large loop excision of the transformation zone (LLETZ) patient choice. End of colposcopy management pathway (for this colposcopy episode). hrHPV positive, cytology high grade or worse, or borderline (endocervical): undertake LLETZ. End of colposcopy management pathway (further management based on findi...

    3. What did the colposcopy examination show?

    Abnormal biopsy showing cervical intra-epithelial neoplasia (CIN)1 or worse, or colposcopic impression of CIN1 (no biopsy): manage as an abnormal colposcopy examination. Go to Flowchart 3 (abnormal colposcopy result management pathway) below. No CIN on biopsy, no biopsy, or no colposcopic impression of CIN: go to question 4.

    1. Abnormal biopsy result: was the result CIN1?

    Yes: the CIN1 pathway only applies to individuals with CIN1 confirmed on biopsy or colposcopic impression of CIN1 (no biopsy) who were referred with low grade cytology, or hrHPVpositive/cytology negative referrals. Recall in 12 months. Go to question 2. No: CIN2, CIN3 or cervical glandular intra-epithelial neoplasia (CGIN): Go to question 6.

    2. Is screening result hrHPV negative or positive?

    hrHPV negative: recall in 36 months. End of abnormal colposcopy result pathway (for this colposcopy episode). If HPV test is negative at 36 months, return to routine screening interval. If HPVtest is positive at 36 months, follow the process outlined in pathway part 1 above. hrHPVpositive: carry out cervical cytology test. Go to question 3.

    3. Is cytology negative or abnormal?

    Cytology negative: recall in 12 months. Go to question 4. Cytology abnormal: refer to colposcopy. End of abnormal colposcopy result pathway (for this colposcopy episode). Further management based on findings from repeat colposcopy.

  2. Jan 15, 2021 · For most patients with abnormal results on Pap and/or HPV tests, management in 2020 is similar to 2012 guidelines. 5,29 Colposcopy is recommended for most patients with positive HPV tests and abnormal Pap tests.

    • Rebecca B Perkins, Richard L Guido, Mona Saraiya, George F Sawaya, Nicolas Wentzensen, Mark Schiffma...
    • 10.1089/jwh.2020.8918
    • 2021
    • January 2021
  3. information and tips to help GP practices identify actions that will result in improved screening coverage, particularly amongst those in underserved communities. This guide is not exhaustive and should be read in conjunction with national guidance. Further resources

  4. The adoption of the USPSTF guidelines expands the recommended options for cervical cancer screening in average-risk individuals aged 30 years and older to include screening every 5 years with primary high-risk human papillomavirus (hrHPV) testing.

  5. The new guidelines provide risk thresholds for clinical action (Table 1) and establish risk estimates for the development of cervical intraepithelial neoplasia grade 3 (CIN 3), adenocarcinoma in situ, or cancer (ie, CIN 3+) for different combinations of test results.

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  7. When will I get the results of my cervical screening? Usually within 2 to 6 weeks. What do the results mean? The test looks for HPV (human papillomavirus). The results will tell you if you have HPV or not. If you have HPV, the results will also tell you whether there are any changes in the cells that could lead to cancer. What happens next?

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