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This review summarizes our current understanding of the major pathway for the initiation phase of protein synthesis in eukaryotic cells, with a focus on recent advances. We describe the major scanning or messenger RNA (mRNA) m7G cap-dependent ...
- Biochemistry, Protein Synthesis - StatPearls - NCBI Bookshelf
Protein factors– the process of protein synthesis requires...
- Biochemistry, Protein Synthesis - StatPearls - NCBI Bookshelf
Jul 17, 2023 · Protein factors– the process of protein synthesis requires multiple non-ribosomal proteins that transiently participate during the initiation, elongation, and termination phases of protein synthesis.
- Jacob E. Hoerter, Steven R. Ellis
- 2023/07/17
- 2021
Relate protein synthesis and its two major phases to the central dogma of molecular biology. Identify the steps of transcription, and summarize what happens during each step. Explain how mRNA is processed before it leaves the nucleus.
Feb 16, 2021 · In bacteria, three translation initiation factors — initiation factor 1 (IF1), IF2 and IF3 — help to recruit initiator tRNA and to localize the start codon on the message 41.
- Eva Kummer, Nenad Ban
- 2021
Dec 3, 2018 · We describe the major scanning or messenger RNA (mRNA) m 7 G cap-dependent mechanism, which is a highly coordinated and stepwise regulated process that requires the combined action of at least 12 distinct translation factors with initiator transfer RNA (tRNA), ribosomes, and mRNAs.
- William C. Merrick, Graham D. Pavitt
- 2018
Jul 21, 2013 · These structures offer insight into the contributions of the initiation factors, the mechanism by which mRNA is scanned, and the interactions that occur in the ribosome's P site.
Transcription and RNA processing are followed by translation, the synthesis of proteins as directed by mRNA templates. Proteins are the active players in most cell processes, implementing the myriad tasks that are directed by the information encoded in genomic DNA.
