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      • The initiation of protein synthesis is the process that results in bringing together an 80S ribosome with a messenger RNA (mRNA) and initiator methionyl-transfer RNA (Met-tRNA i).
      cshperspectives.cshlp.org/content/10/12/a033092.full

      Protein Synthesis Initiation in Eukaryotic Cells - CSHL P

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  3. pmc.ncbi.nlm.nih.gov › articles › PMC6280705Protein Synthesis Initiation in Eukaryotic Cells - PMC

    This review summarizes our current understanding of the major pathway for the initiation phase of protein synthesis in eukaryotic cells, with a focus on recent advances. We describe the major scanning or messenger RNA (mRNA) m7G cap-dependent ...

  4. www.ncbi.nlm.nih.gov › books › NBK545161Biochemistry, Protein Synthesis - StatPearls - NCBI Bookshelf

    Jul 17, 2023 · Protein factors– the process of protein synthesis requires multiple non-ribosomal proteins that transiently participate during the initiation, elongation, and termination phases of protein synthesis.

    • Jacob E. Hoerter, Steven R. Ellis
    • 2023/07/17
    • 2021

  5. pubmed.ncbi.nlm.nih.gov › 29735639Protein Synthesis Initiation in Eukaryotic Cells - PubMed

    Dec 3, 2018 · We describe the major scanning or messenger RNA (mRNA) m 7 G cap-dependent mechanism, which is a highly coordinated and stepwise regulated process that requires the combined action of at least 12 distinct translation factors with initiator transfer RNA (tRNA), ribosomes, and mRNAs.

    • William C. Merrick, Graham D. Pavitt
    • 2018

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  7. www.ncbi.nlm.nih.gov › books › NBK6597Mechanism of Translation Initiation in Eukaryotes - Madame ...

    The initiation of protein synthesis consists in the recruitment of a ribosome·initiator tRNA complex to the initiation codon of a messenger RNA. In prokaryotes, this process involves the direct interaction of the ribosomal RNA with the mRNA.

    • Francis Poulin, Nahum Sonenberg
    • 2013
    • 2013

  8. www.ncbi.nlm.nih.gov › books › NBK9914Protein Synthesis, Processing, and Regulation - The Cell ...

    Transcription and RNA processing are followed by translation, the synthesis of proteins as directed by mRNA templates. Proteins are the active players in most cell processes, implementing the myriad tasks that are directed by the information encoded in genomic DNA.

    • Geoffrey M Cooper
    • 2000
    • 2000

  9. www.nature.com › articles › nrm2838The mechanism of eukaryotic translation initiation and ...

    Protein synthesis is principally regulated at the initiation stage (rather than during elongation or termination), allowing rapid, reversible and spatial control of gene expression.

  10. cshperspectives.cshlp.org › content › 10Protein Synthesis Initiation in Eukaryotic Cells - CSHL P

    The initiation of protein synthesis is the process that results in bringing togetheran 80S ribosome with a messenger RNA (mRNA) and initiator methionyl-transfer RNA (Met-tRNAi).

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