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    • Image courtesy of slideserve.com

      slideserve.com

      • The initiation of protein synthesis is the process that results in bringing together an 80S ribosome with a messenger RNA (mRNA) and initiator methionyl-transfer RNA (Met-tRNA i).
      pmc.ncbi.nlm.nih.gov/articles/PMC6280705/
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  2. The ribosome, the aminoacylated and formylated initiator tRNA (fMet-tRNA f Met), mRNA, and the three protein factors, initiation factor IF1, initiation factor IF2, and initiation factor IF3, are involved in the translation initiation phase (Fig. 1).

  3. Subsequent sections describe the structure, function, and interactions of the mRNA, the initiator tRNA, and the initiation factors IF1, IF2, and IF3. Finally, we provide an overview of mechanisms of regulation of the translation initiation event.

    • Brian Søgaard Laursen, Hans Peter Sørensen, Kim Kusk Mortensen, Hans Uffe Sperling-Petersen
    • 2005
  4. Jul 17, 2023 · Protein factors– the process of protein synthesis requires multiple non-ribosomal proteins that transiently participate during the initiation, elongation, and termination phases of protein synthesis.

    • Jacob E. Hoerter, Steven R. Ellis
    • 2023/07/17
    • 2021
  5. Feb 16, 2021 · In bacteria, three translation initiation factors — initiation factor 1 (IF1), IF2 and IF3 — help to recruit initiator tRNA and to localize the start codon on the message 41.

    • Eva Kummer, Nenad Ban
    • 2021
  6. We present a detailed description of current knowledge about the structure, function, and interactions of the individual components involved in bacterial translation initiation. The first section describes the ribosomal features relevant to the initiation process.

  7. May 9, 2015 · Translation initiation factors, such as eIF3, eIF4A, eIF4E, eIF4G, and eIF5A affect different processes during vegetative and reproductive growth like embryogenesis, xylogenesis, flowering, sporogenesis, pollen germination, etc.

  8. Jan 1, 2024 · Each of these steps is dependent on different sets of accessory protein factors termed initiation factors (IFs), elongation factors (EFs), release factors (RFs), and recycling factor (RRF).