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- The ribosome, the aminoacylated and formylated initiator tRNA (fMet-tRNA fMet), mRNA, and the three protein factors, initiation factor IF1, initiation factor IF2, and initiation factor IF3, are involved in the translation initiation phase (Fig. 1).
www.ncbi.nlm.nih.gov/pmc/articles/PMC1082788/
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The ribosome, the aminoacylated and formylated initiator tRNA (fMet-tRNA f Met), mRNA, and the three protein factors, initiation factor IF1, initiation factor IF2, and initiation factor IF3, are involved in the translation initiation phase (Fig. (Fig.1 1).
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IF2 Interactions with fMet-tRNA f Met and the ribosome. (A)...
- Fig.7 7
Initiation factor IF1 and structural homologues. ( A )...
- PMC Free Article
Ribosomal protein S1 stimulates translation initiation in...
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Jul 17, 2023 · Protein factors– the process of protein synthesis requires multiple non-ribosomal proteins that transiently participate during the initiation, elongation, and termination phases of protein synthesis. These factors are named for the phase in which they function (for example, eukaryotic initiation factor 2, eIF2).
- Jacob E. Hoerter, Steven R. Ellis
- 2023/07/17
- 2021
We present a detailed description of current knowledge about the structure, function, and interactions of the individual components involved in bacterial translation initiation. The first section describes the ribosomal features relevant to the initiation process.
The first section describes the ribosomal features relevant to the initiation process. Subsequent sections describe the structure, function, and interactions of the mRNA, the initiator tRNA, and the initiation factors IF1, IF2, and IF3.
- Brian Søgaard Laursen, Hans Peter Sørensen, Kim Kusk Mortensen, Hans Uffe Sperling-Petersen
- 2005
Apr 21, 2024 · The initiation of protein synthesis begins with the formation of an initiation complex. In E. coli , this complex involves the small 30S ribosome, the mRNA template, three initiation factors that help the ribosome assemble correctly, guanosine triphosphate (GTP) that acts as an energy source, and a special initiator tRNA carrying N -formyl ...
Jan 1, 2024 · The first one introduces the general steps of protein synthesis in prokaryotes, with a focus on mechanistic details of translation initiation, elongation, termination and ribosome recycling, and on the functional roles of individual translation factors involved in these steps.
The initiation of protein synthesis is the process that results in bringing together an 80S ribosome with a messenger RNA (mRNA) and initiator methionyl-transfer RNA (Met-tRNA i).
