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Which protein factors are involved in translation initiation in bacteria?
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The ribosome, the aminoacylated and formylated initiator tRNA (fMet-tRNA f Met), mRNA, and the three protein factors, initiation factor IF1, initiation factor IF2, and initiation factor IF3, are involved in the translation initiation phase (Fig. (Fig.1 1).
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IF2 Interactions with fMet-tRNA f Met and the ribosome. (A)...
- Fig.7 7
Initiation factor IF1 and structural homologues. (A)...
- PMC Free Article
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We present a detailed description of current knowledge about the structure, function, and interactions of the individual components involved in bacterial translation initiation. The first section describes the ribosomal features relevant to the initiation process.
Jul 17, 2023 · Protein factors– the process of protein synthesis requires multiple non-ribosomal proteins that transiently participate during the initiation, elongation, and termination phases of protein synthesis.
- Jacob E. Hoerter, Steven R. Ellis
- 2023/07/17
- 2021
The first section describes the ribosomal features relevant to the initiation process. Subsequent sections describe the structure, function, and interactions of the mRNA, the initiator tRNA, and the initiation factors IF1, IF2, and IF3.
- Brian Søgaard Laursen, Hans Peter Sørensen, Kim Kusk Mortensen, Hans Uffe Sperling-Petersen
- 2005
Jan 1, 2024 · The first one introduces the general steps of protein synthesis in prokaryotes, with a focus on mechanistic details of translation initiation, elongation, termination and ribosome recycling, and on the functional roles of individual translation factors involved in these steps.
Sep 1, 2023 · In response to stress conditions or nutrient depletion, bacterial cells reduce ribosome biogenesis, modify ribosomes and components of the translational machinery, and regulate translation initiation and elongation for adapting protein synthesis to changing conditions (Fig. 1).
Figure 11.15 Translation in bacteria begins with the formation of the initiation complex, which includes the small ribosomal subunit, the mRNA, the initiator tRNA carrying N-formyl-methionine, and initiation factors. Then the 50S subunit binds, forming an intact ribosome. Diagram showing translation.
