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  1. Oct 30, 2019 · Furthermore, the most recently updated guideline included in our study, the 2018 American College of Cardiology/American Heart Association (ACC/AHA) guideline on management of blood cholesterol, is the first guideline to include an extensive discussion on statin discontinuation and age-related complexities in the preventive treatment of older adults. 32 It was unique in using the terms ...

    • Milly A. van der Ploeg, Carmen Floriani, Wilco P. Achterberg, Jonathan M.K. Bogaerts, Jacobijn Gusse...
    • 42
    • 2020
    • 30 October 2019
  2. Aug 25, 2022 · People aged over 80 years who stop taking statins may have substantially reduced protection against cardiovascular disease (CVD), suggests a large data analysis from over 150,000 people. The modelling study, carried out by researchers from Queen Mary University of London, the University of Oxford and the University of Sydney, found that people with lower CVD […]

    • The Research
    • The BHF View
    • How The Research Was Reported

    The study was carried out by researchers at the University of Girona in Spain and was published in the British Medical Journal. A limitation of the study is that it was ‘observational’, meaning that the researchers collected retrospective data about patients from their healthcare records. This means that other factors could have influenced the resu...

    Professor Jeremy Pearson, Associate Medical Director at the British Heart Foundation, said:“Old age itself – particularly reaching the age of 80 and above - puts people at increased risk of a heart attack or stroke. This risk can be heightened by factors such as high cholesterol, diabetes and high blood pressure, even in those who are otherwise see...

    Media coverage of the study focussed on the results finding no benefit for the ‘healthy’ over-75s taking statins to reduce their risk of heart disease and stroke. The Mirror reported “Statins 'have no benefit' for thousands of healthy older people taking them”, while the Daily Mailconcluded “Millions given statins 'just in case' are wasting their t...

  3. Feb 1, 2024 · Participants began taking one of two different statin drugs, simvastatin (Zocor) or atorvastatin (Lipitor), between 2008 and 2018. The study found that the people most likely to have their LDL cholesterol lowered by statin drugs were those older than 75. So, statins remain effective at lowering cholesterol in people older than 75.

    • Anthony L. Komaroff, MD
    • hhp_info@health.harvard.edu
  4. Jul 25, 2024 · Contemporary clinical guidance discusses statin discontinuation among older adults, particularly those >75 years of age. 55, 56 This is in part because there are limited data on the benefits of statins in adults aged over 75 years. 57, 58 Given the limited evidence, the decision to continue or stop a statin should be considered as a preference-sensitive decision, whereby a person's individual ...

    • 25 July 2024
  5. Jun 28, 2016 · With respect to older patients, a review has noted that other conditions in the older population might affect statin metabolism or cause similar side effects, thus changing the statin pharmacokinetics for this group.27 In particular, muscular side effects have been shown elsewhere to be important in older patients treated with statins.28 The association between liver disease and increased risk ...

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  7. Most people can continue drinking alcohol while taking a statin if they chose to. But people who regularly drink a large amount have an increased risk of side effects and liver problems. Also, if you’re prescribed a statin it’s because your risk of a heart condition, such as heart attack or stroke, is higher.

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