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  1. Jan 17, 2022 · In Canada and the United States, the results of a Pap test are divided into three categories: Normal; Abnormal; Inadequate; Normal. If your pap smear is normal, your result will say negative for intraepithelial lesion or malignancy. Normal cells need to be seen in order to make this diagnosis.

  2. Apr 30, 2022 · The Bethesda System (TBS) stands out as a model of standardized reporting in cervicovaginal cytology. Apart from its reproducibility, it reflects the most current understanding of cervical cancer. The most important feature is its clinical relevance.

    • Normal Pap smear. A normal Pap smear reading means that there are no cell lesions or malignancy noted. Note that although Pap smears are a very good tool, they are not perfect — and false negatives do occur, which is yet another good reason to get regular screening.
    • ASCUS. ASCUS is a relatively common abnormal Pap test result indicating “atypical cells of undetermined significance.” This is a slightly irregular reading.
    • LGSIL. LGSIL, the next grade of cellular abnormality, designates a “low–grade squamous intraepithelial lesion.” This low–grade lesion is seen as an indication that a high-grade HPV viral strain is likely causing abnormal cell features.
    • HGSIL. HGSIL indicates a “high–grade intraepithelial lesion” and is of greater concern, as the HPV virus is likely to be causing moderate to severe changes of the cervix.
  3. Jul 10, 2006 · Discover the most common abnormal Pap smear causes, including HPV, cervical dysplasia, and more. Learn what each result means and the next steps to take.

  4. Moderate to severe cervical cell changes are classified in the Bethesda system (TBS) as high-grade squamous intraepithelial lesions (HSIL) or atypical glandular cells (AGC). Follow-up evaluation is needed, and treatment may be needed.

  5. Jun 6, 2024 · Follow-up tests and procedures after an abnormal Pap test (Pap smear) or HPV test. Treatment for high-grade cervical cell changes. HPV test results: What positive and negative results on a screening test mean. HPV test results show whether high-risk HPV types were found in cervical cells.

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  7. May 1, 2015 · Although TBS was developed primarily for cervical cytology, specimens from other sites in the lower anogenital tract, such as the vagina and anus, could also be reported using this terminology.

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