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  1. Jul 16, 2015 · While generally safe and effective when prescribed by a veterinarian, flunixin can cause side effects in some animals. The most common adverse effects associated with flunixin are vomiting, diarrhea, lethargy, and lack of appetite.

    • Piperazine

      The most common adverse effects associated with piperazine...

    • The Quest Study
    • The Epic Study
    • Pimobendan Side Effects
    • Help! Pimobendan Killed My Dog!
    • When Should My Dog Take Pimobendan?
    • Update: Mitral Valve Repair
    • References

    252 dogs with naturally occurring MMVD and congestive heart failure were divided into two groups: one taking pimobendan and another taking benazepril, the leading heart treatment at the time. Both were allowed other treatments as needed. They were then studied over the following years until one of the following three things happened: 1. sudden deat...

    To my knowledge, the EPIC study was the first in veterinary medicine to be stopped early because of what was found. 354 dogs were chosen who had MMVD but were not yet in heart failure. At this earlier stage they had enlarged hearts as determined by xray and ultrasound. Up to the time of the study, treatment was not believed to help at this stage, a...

    Similar rates of adverse effects were reported for pimobendan and benazepril. This suggests that the drug is at least as safe as other heart treatments, Pimobendan also recorded similar side effects to the placebo. Deaths in the pimobendan group were 46.4% versus 57.2% in the placebo group. This suggests that pimobendan is safe compared with any dr...

    What then do we make of online reports of terrible events after dogs took pimobendan? The high rates of death and side effects in the placebo group provide the best clue. These are old dogs with a high risk of illness from any cause. We humans are notoriously bad at separating causation from correlation. In fact, with any one dog, it’s virtually im...

    Pimobendan is a much better drug at stopping dogs going into heart failure than it is in treating them once they do. So here’s a quick summary of how to use pimobendan in 2022 and beyond: 1. Get regular checkups (at least annually) to look for early signs of heart disease. This is mainly the appearance of a heart murmur. 2. Once a murmur appears, w...

    I hesitate to add this as I fear giving dog owners false hope, but several comments below have spurred me to also discuss the surgical option. As of 2023, there are now several centres around the world that offer open heart surgery to improve mitral valve function. It is not replacement of the valve, but instead modifying its shape or adding suppor...

    Boswood, A., Häggström, J., Gordon, S. G., Wess, G., Stepien, R. L., Oyama, M. A., … & Watson, P. (2016). Effect of pimobendan in dogs with preclinical myxomatous mitral valve disease and cardiomegaly: the EPIC study—a randomized clinical trial. Journal of Veterinary Internal Medicine 30,(6), 1765-1779. Full Article. Häggström, J., Boswood, A., O’g...

  2. Sep 16, 2024 · What Are the Common Side Effects of Vetmedin? 🤔. While Vetmedin is generally well-tolerated, some dogs may experience side effects. Common ones include: Gastrointestinal Issues: Loss of Appetite: Your dog may eat less than usual. Diarrhea: Loose stools can occur. Vomiting: Some dogs may vomit after dosing. Lethargy:

  3. Nov 28, 2023 · Deworming your dog is important because parasites deprive your dog of important vitamins and minerals. As with all medications, there is a possibility of side effects. Read on to learn what to expect.

  4. Urethral sphincter mechanism incompetence (USMI) is the most common cause of urinary incontinence in spayed female dogs.1 Studies have estimated the prevalence of USMI in dogs to be between 5.1% and 20%, with large-breed dogs being predisposed.1-3 While the pathophysiology of USMI is multifactorial, medical management is often directed at increa...

  5. Jan 11, 2024 · What is Cerenia used for in dogs and cats? Cerenia is used in cases of nausea and vomiting. It’s commonly used for: Motion sickness: If your pet gets queasy during car rides or travels, Cerenia can prevent motion sickness, ensuring a smoother journey for your furry friend.

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  7. Sep 25, 2019 · Side Effects of Pimobendan in Dogs. The most commonly observed pimobendan side-effects include vomiting, diarrhea, loss of appetite, lethargy, fainting, weakness, poor coordination, breathing difficulties (coughing and wheezing) and tachycardia (rapid heart rate).

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