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  1. The eradication of a disease is a global and permanent achievement, while the elimination of a disease relates to a specific geographic area.1. Eradication means that intervention measures are no longer required, and the agent that previously caused the disease is no longer present.

    • Max Roser, Sophie Ochmann, Hannah Behrens, Hannah Ritchie, Bernadeta Dadonaite
    • 2014
  2. Mar 10, 2012 · A history of eradication—successes, failures, and controversies. On May 8, 1980, the World Health Assembly endorsed a historic resolution, which declared “that the world and all its peoples have won freedom from smallpox”. Smallpox was the first and, so far, the only human disease to have been eradicated.

    • Donald A Henderson
    • 2012
  3. Oct 2, 2024 · The celebrated 1980 announcement that smallpox had been eradicated was made using the following definition of eradication: “Permanent reduction to zero of the worldwide incidence of infection caused by a specific agent as a result of deliberate efforts: intervention measures are no longer needed.” Public health around the world works with this definition of “eradication,” setting it as ...

  4. The eradication of infectious diseases is the reduction of the prevalence of an infectious disease in the global host population to zero. [1] Two infectious diseases have successfully been eradicated: smallpox in humans, and rinderpest in ruminants. There are four ongoing programs, targeting the human diseases poliomyelitis (polio), yaws ...

  5. May 12, 2021 · Hope for an eradication akin to smallpox – or even a polio- or measles-style elimination – is a towering aspiration. Herd immunity, meanwhile, is a moving target that requires a lot of things ...

  6. Eradication of an infectious disease is an extraordinary goal. Its possibility became apparent as soon as Edward Jenner demonstrated an ability to provide immunity to smallpox. Writing in 1801, Jenner observed that, through broad application of vaccination, "it now becomes too manifest to admit of controversy that the annihilation of the Small Pox, the most dreadful scourge of the human ...

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  8. The concept of “disease eradication” originated in the late 18th century, when Edward Jenner inoculated James Phipps with the cowpox virus and subsequently infected him with the lethal smallpox virus. The inoculation protected Phipps from the smallpox, demonstrating the first successful vaccination against an infectious disease. Jenner concluded, “This practice would wipe out this ...

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