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  1. Apr 5, 2024 · The number of opioid-related deaths has been rising continuously since 1999. Three distinct waves of increases are related to different types of opioids throughout the last 25 years. Increasing communities' support, capacity, and education may help turn the tide and prevent overdose deaths.

  2. The United States opioid epidemic is a nationwide public health crisis. Initially driven by increased consumption and availability of pharmaceutical opioids, an increasing number of opioid overdoses are now related to heroin and illicitly manufactured fentanyl and fentanyl analogs.

    • Jennifer Lyden, Jennifer Lyden, Ingrid A. Binswanger
    • 2019
  3. Jul 10, 2023 · The search criteria included a range of relevant keywords such as "contributing factors of the opioid epidemic", "negative consequences of the opioid epidemic", and "best practices for healthcare providers in managing the opioid epidemic".

  4. Sep 15, 2019 · Our paper makes an important and unique contribution to the burgeoning empirical literature on the opioid epidemic by analyzing the latest drug overdose mortality trends for the US and by presenting a selective but comprehensive review of the literature on drug overdose and opioid-related outcomes.

    • Gopal K Singh, Isaac E Kim, Mehrete Girmay, Chrisp Perry, Gem P Daus, Ivy P Vedamuthu, Andrew A De L...
    • 10.21106/ijma.284
    • 2019
    • Int J MCH AIDS. 2019; 8(2): 89-100.
  5. Nov 15, 2021 · From 1999 to 2019, approximately 500 000 Americans have died because of a drug overdose involving an opioid. 1 The opioid epidemic started in the 1990s when opioids were being prescribed in large quantities after minor injuries or surgical and dental procedures.

    • Enas S Kandil
    • 2021
  6. There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating out of both medical prescriptions and illegal sources. It has been called "one of the most devastating public health catastrophes of our time". The opioid epidemic unfolded in three waves.

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  8. Sep 6, 2024 · Abstract. We examined a natural history of opioid overdose deaths from 1999-2021 in the United States to describe state-level spatio-temporal heterogeneity in the waves of the epidemic. We obtained overdose death counts by state from 1999-2021, categorized as involving prescription opioids, heroin, synthetic opioids, or unspecified drugs.

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