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Dr Sinead Wang is the team lead for the Community Geriatrics workgroup within Singhealth Polyclinics (SHP). She is also an Clinical Assistant Professor for the Duke-NUS Family Medicine Programme.
Conclusions: PRECISE (Predictive Risk scorE for CAD In Southeast Asians with chEst pain) performs well and demonstrates utility as a clinical decision support for diagnosing CAD among Southeast Asians. Keywords: Asian; chest pain; coronary artery disease; primary care; risk score.
- Zhen Sinead Wang, Zhen Sinead Wang, Jonathan Yap, Yi Ling Eileen Koh, Shaw Yang Chia, N Nivedita, Te...
- 2021
- Study Sites
- Participants
- Study Procedure
- Definition of Predictors
- Outcome Measures
- Risk Instruments Tested
- Sample Size Calculation
- Statistical Analysis
Singapore is an urbanized island-state in Southeast Asia with a multi-ethnic population of 5.7 million6. SingHealth Polyclinics (SHP) is a provider of subsidized primary healthcare services. Its network of eight polyclinics covered 1.8 million attendances in 20187. Its affiliate, the National Heart Centre Singapore (NHCS), is the largest local tert...
A prospective cohort study was conducted on consecutive patients who attended all SHP branch clinics for chest pain. They were stable clinically and were subsequently referred for cardiac evaluation at NHCS between July 2013 and December 2016. Those with (a) existing or prior history of CAD, (b) acute coronary syndrome such as unstable angina and e...
Patients completed an interviewer-administered questionnaire and underwent resting electrocardiogram (ECG). Electronic medical records (EMR) were accessed to determine clinical history and laboratory test results. Patients without investigations in the preceding year had fasting blood tests taken upon enrolment to determine their lipid and glucose ...
Chest pain was classified clinically as typical, atypical, or non-anginal8. Patients indicated on a diagram the region of their chest discomfort. To determine if chest pain was reproducible upon palpation, a trained investigator palpated the same area in which the discomfort was reported. Diagnoses of type 2 diabetes mellitus (T2DM), hypertension, ...
The primary outcome was diagnosis of significant CAD, defined as (a) ≥ 70% luminal stenosis of at least one major coronary artery or ≥ 50% left main stenosis (based on either catheter-based or CT coronary angiography), or (b) clinical diagnosis of CAD in patients without coronary angiography. All clinical diagnoses were independently adjudicated by...
The Duke Clinical Score (DCS) predicts critical ischemia (≥ 75% coronary stenosis, or significant left main stenosis). The score was derived from a single tertiary center cohort of patients presenting with chest pain, and who underwent cardiac catheterization between 1969 and 19792. The CAD Consortium Score (CCS) was developed from a pre-existing d...
We envisioned our clinical prediction rule to contain about 10 predictors. Using the rule of thumb of 10 events per predictor, 100 cases of CAD would be needed. CAD prevalence was estimated to be 10%. A 35% dropout was factored. The calculated sample size was 1350. We aimed to recruit an additional 600 patients to allow for internal validation.
The cohort’s baseline characteristics were summarized as frequencies and percentages for categorical variables and mean ± standard deviation (SD) for continuous variables.
- Zhen Sinead Wang, Zhen Sinead Wang, Jonathan Yap, Yi Ling Eileen Koh, Shaw Yang Chia, N Nivedita, Te...
- 2021
Department Name : Family Medicine. Visiting Hour : By Appointment Only. Appointment : +65 6643 6969 & Online Appointment Here. Clinic Details : SingHealth Polyclinics, 167 Jalan Bukit Merah Connection One (Tower 5), #15-10, Singapore 150167. General Enquiries : +65 6236 4800.
SingHealth Polyclinics, Singapore, Singapore, Republic of Singapore. sinead.wang.zhen@singhealth.com.sg. J Gen Intern Med. 2021 Jun 1; 36 (6): 1514-1524. Background Coronary artery disease (CAD) risk prediction tools are useful decision supports.
Dr. Ben Wang Specialist Dental Group 3 Mount Elizabeth, Mount Elizabeth Medical Centre, #08 – 10, Singapore 228510 Tel: 67349393 [/column_quarter_last]
Cardiologists - Mount Elizabeth Medical Centre - Private Healthcare In Singapore. Select Specialty Areas. Cardiologists diagnose, treat, and help to prevent diseases such as stroke, heart failure, and heart attacks that affect the heart and the blood vessels.
