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1. www.ahajournals.org › doi › 10Statin Use in Pregnancy: Is It Time For a Paradigm Shift?

   www.ahajournals.org › doi › 10

   Feb 14, 2022 · Statin deferral during pregnancy in those with FH is controversial, with some studies suggesting adverse vascular consequences from high cholesterol exposure during the relatively short pregnancy period.

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3. www.bmj.com › content › 381Hypertensive disorders of pregnancy - The BMJ

   www.bmj.com › content › 381

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   Jun 30, 2023 · Importantly, a wealth of epidemiological data now links HDP to future cardiovascular disease and diabetes decades after an affected pregnancy. This review discusses the current guidelines and research data on the prevention, diagnosis, management, and postnatal follow-up of HDP.

4. www.amjmed.com › article › S0002-9343(22)00673-8Update on Statin Use in Pregnancy - The American Journal of ...

   www.amjmed.com › article › S0002-9343(22)00673-8

   Sep 20, 2022 · In July 2021, the US Food and Drug Administration (FDA) requested the removal of the long-standing contraindication to statin use in women who are pregnant or contemplating pregnancy.

5. www.ahajournals.org › doi › epdfHypertension in Pregnancy: Diagnosis, Blood Pressure Goals ...

   www.ahajournals.org › doi › epdf

   This report is based on a review of current literature and includes normal physiological changes in pregnancy that may affect clinical presentation of HDP; HDP epidemiology and the immediate and long-term sequelae of HDP; the pathophysiology of preeclampsia, an HDP commonly associated with proteinuria and increasingly recognized as a heterogeneo...

6. www.amjmed.com › article › S0002-9343(22)00673-8Update on Statin Use in Pregnancy - The American Journal of ...

   www.amjmed.com › article › S0002-9343(22)00673-8

   In July 2021, the US Food and Drug Administration (FDA) requested the removal of the long-standing contra-indication to statin use in women who are pregnant or con-templating pregnancy.

7. www.ahajournals.org › doi › 10Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals ...

   www.ahajournals.org › doi › 10

   Dec 15, 2021 · This report is based on a review of current literature and includes normal physiological changes in pregnancy that may affect clinical presentation of HDP; HDP epidemiology and the immediate and long-term sequelae of HDP; the pathophysiology of preeclampsia, an HDP commonly associated with proteinuria and increasingly recognized as a ...

8. People also ask

   Is statin a contraindication for pregnant women?

   • In July 2021, the US Food and Drug Administration (FDA) requested the removal of the long-standing contraindication to statin use in women who are pregnant or contemplating pregnancy.

   Update on Statin Use in Pregnancy - The American Journal of Medicine

   www.amjmed.com/article/S0002-9343(22)00673-8/fulltext

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   Can a pregnant woman with FH get a statin deferral?

   • Statin deferral during pregnancy in those with FH is controversial, with some studies suggesting adverse vascular consequences from high cholesterol exposure during the relatively short pregnancy period. Maternal hypercholesterolemia may affect early atherosclerosis development in offspring through complex mechanisms like genetic programming.

   Statin Use in Pregnancy: Is It Time For a Paradigm Shift?

   www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.058983

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   Can I get pregnant with statins If I have hypercholesterolemia?

   • Instead, statins are allowed for women with familial hypercholesterolemia, other severe LDL-C increases, or established (prior) ASCVD whenever the benefits are judged to outweigh any risks. We suggest that inadvertent conception during statin therapy does not require pregnancy termination but should prompt close follow-up with an obstetrician.

   Update on Statin Use in Pregnancy - The American Journal of Medicine

   www.amjmed.com/article/S0002-9343(22)00673-8/fulltext

   See all results for this question

   Are hydrophilic statins safe during pregnancy?

   • The apparently lower risk with hydrophilic statins may be due to a lower tendency to cross the placenta. 17 Unexpectedly, adverse neonatal outcomes were less likely in a subgroup of 174 women who continued statins throughout pregnancy compared to 395 women who discontinued statins after conception was confirmed. 16

   Update on Statin Use in Pregnancy - The American Journal of Medicine

   www.amjmed.com/article/S0002-9343(22)00673-8/fulltext

   See all results for this question

   Are Statins safe during pregnancy?

   • The intent of the recent FDA recommendation on statins was not to approve statin use in all pregnant patients. Rather, the goal was to revise the language to reassure clinicians that in certain individuals, especially very high-risk patients, continuing statin therapy through pregnancy may be beneficial.

   Statin Use in Pregnancy: Is It Time For a Paradigm Shift?

   www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.058983

   See all results for this question

   Should pregnant women discontinue statin therapy?

   • The FDA language was likely purposefully vague, allowing latitude in shared decision-making: “Health care professionals should discontinue statin therapy in most pregnant patients, or they can consider the ongoing therapeutic needs of the individual patient, particularly those at very high risk for cardiovascular events during pregnancy.”

   Statin Use in Pregnancy: Is It Time For a Paradigm Shift?

   www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.058983

   See all results for this question

9. newsroom.heart.org › news › high-blood-pressureHigh blood pressure treatment in pregnancy is safe, prevents ...

   newsroom.heart.org › news › high-blood-pressure

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   Dec 15, 2021 · DALLAS, Dec. 15, 2021 — Treatment for high blood pressure during pregnancy appears safe for many women and may reduce maternal risk for severe hypertension without increasing fetal and neonatal risks, according to a new American Heart Association scientific statement published today in the Association’s journal Hypertension.