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1. • • In patients with type 2 diabetes mellitus, statin use is associated with a small increase in hemoglobin A1c, and this effect may be greater with atorvastatin than with other statins. However, the benefits of statins in preventing atherosclerotic cardiovascular disease outweigh their adverse effects on glycemic control.
     www.ccjm.org/content/90/1/53

     Statins may increase diabetes, but benefit still outweighs risk

2. People also ask

   Does statin therapy increase the risk of diabetes?

   • The clinical trials that defined the diabetes risk have been relatively short-term, yet statin therapy is often continued for years; thus, it's possible that the risk of diabetes will increase with the duration of follow-up.

   Statins: Is It Really Time to Reassess Benefits and Risks?

   www.nejm.org/doi/full/10.1056/NEJMp1203020

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   Do you need a statin if you have diabetes?

   • You might be prescribed a statin if: you’re at risk of developing heart disease, or you have cardiovascular disease. Statins are often prescribed for adults with diabetes because living with diabetes increases the risk of heart attack and stroke. Many people with type 1 diabetes are prescribed a statin to prevent heart disease.

   Statins and diabetes | Diabetes UK

   www.diabetes.org.uk/about-diabetes/looking-after-diabetes/treatments/tablets-and-medication/statins

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   Does statin treatment reduce cardiovascular disease risk?

   • Dear Editor Diabetes has been consistently shown to be associated with an increased risk for cardiovascular disease, and many clinical trials have shown that statin treatment is associated with a reduction in cardiovascular disease risk.

   Risk of diabetes with statins - The BMJ

   www.bmj.com/content/381/bmj-2022-071727/rr-0

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   Do statins reduce non-HDL-C levels in patients with diabetes?

   • Our review assessed the efficacy of the most prescribed statin treatments at different intensities in reducing levels of non-HDL-C in patients with diabetes. Our analysis used robust methods, including bayesian meta-analysis and rigorous quality assessment by CINeMA. Our study had several limitations.

   Comparative effectiveness of statins on non-high density lipoprotein

   www.bmj.com/content/376/bmj-2021-067731

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   Can statins be used to treat dyslipidemia in diabetic patients?

   • Although diabetes is a serious health concern, the management of dyslipidemia with statins substantially reduces cardiovascular risk and improves survival; thus, current data do not support the discontinuation of statins when diabetes is diagnosed, and it remains prudent to target lipid levels according to established guidelines.

   Statins: Is It Really Time to Reassess Benefits and Risks?

   www.nejm.org/doi/full/10.1056/NEJMp1203020

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   Does statin use increase the risk of diabetes in postmenopausal women?

   • Statin medication use in postmenopausal women is associated with an increased risk for DM. This may be a medication class effect however further studies by statin type and dose may reveal varying risk levels for new-onset DM in this population. (7) Statin use was significantly associated with an increased risk of new-onset type 2 diabetes.

   Risk of diabetes with statins - The BMJ

   www.bmj.com/content/381/bmj-2022-071727/rr-0

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3. www.nejm.org › doi › fullStatins: Is It Really Time to Reassess Benefits and Risks?

   www.nejm.org › doi › full

   May 10, 2012 · A meta-analysis of six statin trials that included 57,593 participants revealed a 13% increase in the relative risk of new-onset diabetes 3 — a more modest effect than that seen in the...

   • Author: Allison B Goldfine

   • Publish Year: 2012

4. www.bbc.co.uk › should-i-take-statinsBBC Two - Trust Me, I'm a Doctor, Series 1 - Should I take ...

   www.bbc.co.uk › should-i-take-statins

   Should I take statins? Michael Mosley talks to two experts with very different opinions on whether we should take statins to reduce our risk of a heart attack or stroke. Statins reduce...

5. www.bmj.com › content › 376Comparative effectiveness of statins on non-high density ...

   www.bmj.com › content › 376

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   Mar 24, 2022 · Our review assessed the efficacy of the most prescribed statin treatments at different intensities in reducing levels of non-HDL-C in patients with diabetes. Our analysis used robust methods, including bayesian meta-analysis and rigorous quality assessment by CINeMA.

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7. www.bmj.com › content › 381Risk of diabetes with statins - The BMJ

   www.bmj.com › content › 381

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   May 12, 2023 · Diabetes has been consistently shown to be associated with an increased risk for cardiovascular disease, and many clinical trials have shown that statin treatment is associated with a reduction in cardiovascular disease risk.

8. pmc.ncbi.nlm.nih.gov › articles › PMC2752935Statin Therapy and Risk of Developing Type 2 Diabetes: A Meta ...

   pmc.ncbi.nlm.nih.gov › articles › PMC2752935

   However, the relationship of statin therapy to incident type 2 diabetes is controversial. In the first study that evaluated this association using the West of Scotland Coronary Prevention Study (WOSCOPS) published in 2001, pravastatin at 40 mg/day was reported to be associated with a 30% risk reduction for incident diabetes, although the upper ...

9. www.thelancet.com › journals › landiaEffects of statin therapy on diagnoses of new-onset diabetes ...

   www.thelancet.com › journals › landia

   Mar 27, 2024 · Meta-analyses assessed the effects of allocation to statin therapy on new-onset diabetes (defined by diabetes-related adverse events, use of new glucose-lowering medications, glucose concentrations, or HbA 1c values) and on worsening glycaemia in people with diabetes (defined by complications of glucose control, increased use of glucose-lowering...

10. www.diabetes.org.uk › statinsStatins and diabetes | Diabetes UK

    www.diabetes.org.uk › statins

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    Statins are a type of medication that help to lower your bad cholesterol. If you live with diabetes, then you might be prescribed a statin to lower your risk of heart attack and stroke.