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    • Nucleus

      Image courtesy of tes.com

      tes.com

      • It happens in the S phase of cell division. DNA must replicate before cells divide so that the two resulting daughter cells contain the same genetic information as the parent cell. DNA replication occurs in the nucleus of all eukaryotic cells and the nucleoid of prokaryotes.
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  2. In this section, we discuss how DNA replication is initiated and how cells carefully regulate this process to ensure that it takes place at the proper positions on the chromosome and also at the appropriate time in the life of the cell.

    • Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter
    • 2002
    • 2002
    • Initiation
    • Elongation
    • Termination

    DNA synthesis is initiated at particular points within the DNA strand known as ‘origins’, which have specific coding regions. These origins are targeted by initiator proteins, which go on to recruit more proteins that help aid the replication process, forming a replication complex around the DNA origin. Multiple origin sites exist within the DNA’s ...

    Once DNA Polymerase has attached to the two unzipped strands of DNA (i.e. the template strands), it is able to start synthesising new strands of DNA to match the templates. DNA polymerase is only able to extend the primer by adding free nucleotides to the 3’ end. One of the template strands is read in a 3’ to 5’ direction, therefore the new strand ...

    The process of expanding the new DNA strands continues until there is either no more DNA template strand left to replicate (i.e. at the end of the chromosome) or two replication forks meet and subsequently terminate.The meeting of two replication forks is not regulated and happens randomly along the course of the chromosome. Once DNA synthesis has ...

  3. Mar 17, 2022 · The replication of DNA occurs during the synthesis phase, or S phase, of the cell cycle, before the cell enters mitosis or meiosis. The elucidation of the structure of the double helix provided a hint as to how DNA is copied.

  4. Feb 17, 2023 · DNA replication is the process through which a cell’s DNA forms two exact copies of itself. It occurs in all living organisms as it forms the basis of inheritance in all living organisms. The enzyme carrying out transcription is called DNA polymerase. The primary mechanism of DNA replication is similar across all organisms.

  5. Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).

  6. The helix structure is unwound. Special molecules break the weak hydrogen bonds between bases, which are holding the two strands together. This process occurs at several locations on a DNA...

  7. Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment....

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