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Within eukaryotes, DNA replication is controlled within the context of the cell cycle. As the cell grows and divides, it progresses through stages in the cell cycle; DNA replication takes place during the S phase (synthesis phase).
Mar 17, 2022 · The replication of DNA occurs during the synthesis phase, or S phase, of the cell cycle, before the cell enters mitosis or meiosis. The elucidation of the structure of the double helix provided a hint as to how DNA is copied.
Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment....
Feb 17, 2023 · Step 1: Initiation. Unzipping of DNA. DNA replication starts at a particular location on the DNA, called the origin of replication. It is the region where the DNA is unzipped. They have a specific sequence covering about 245 base pairs, mostly A/T base pairs and fewer GT-base pairs.
Jun 2, 2024 · Step 1: Initiation. The point at which the replication begins is known as the Origin of Replication (oriC). Helicase brings about the procedure of strand separation, which leads to the formation of the replication fork. Step 2: Elongation.
- Vikrant Shetty
- 5 min
Apr 8, 2024 · Initiation. DNA synthesis is initiated at particular points within the DNA strand known as ‘origins’, which have specific coding regions. These origins are targeted by initiator proteins, which go on to recruit more proteins that help aid the replication process, forming a replication complex around the DNA origin.
In this section, we discuss how DNA replication is initiated and how cells carefully regulate this process to ensure that it takes place at the proper positions on the chromosome and also at the appropriate time in the life of the cell.
