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Mar 5, 2024 · Athletes are more prone to the development of statin-associated muscle symptoms (SAMS); however, there is inconclusive evidence to support a pathophysiologic effect of statins on muscle weakness or reduced aerobic capacity.
Despite the salutary effects, there are some unintended consequences of statins, including being linked to muscle pain, cramps, and fatigue, which may lead to reduced levels of physical activity (PA) and/or structured aerobic exercise.
- Barry A. Franklin, Carl J. Lavie
- 2015
Mar 23, 2017 · Statins may increase exercise-related muscle complaints and muscle enzymes. •. Statins do not consistently reduce strength, endurance, exercise, or activity. •. Link between statins, exercise, myalgia, or decrease in exercise may exist. •. No correlation with intensity of statin and effect on exercise, myalgia, or exercise. Abstract. Objective.
- Adam M. Noyes, Paul D. Thompson
- 2017
Simultaneously, physical activity is increasingly recognized and recommended to reduce CVD risk. 9 Statin-associated musculoskeletal side effects, exacerbated by recommended physical activity, could lead to reduced statin use in individuals who would benefit from statin therapy. This review explores mechanisms that may increase the risk of ...
May 19, 2022 · Recent reviewers have summarized evidence indicating that improvements in CRF play an integral role in reducing not only CVD but also incident myocardial infarction, hypertension, diabetes, atrial fibrillation, heart failure, stroke, and all-cause mortality (13, 14).
Feb 24, 2021 · We describe the results of StatinWISE (Statin Web-based Investigation of Side Effects), a series of n-of-1 trials comparing treatment periods of statins and placebo in people who had previously reported muscle symptoms when taking statins.
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Jan 24, 2024 · Literature on statin side effects, red flags controversies, practical tips, and non-statin options for lowering LDL-C levels was also critically reviewed and discussed in this manuscript.
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