Yahoo Web Search

Search results

1. • • The NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study was conducted to determine the effectiveness of different treatments for people with major depression who have not responded to initial treatment with an antidepressant. This is the largest and longest study ever conducted to evaluate depression treatment.
     www.nimh.nih.gov/funding/clinical-research/practical/stard

     Sequenced Treatment Alternatives to Relieve Depression (STAR ...

2. People also ask

   Is STAR*d a good antidepressant?

   • STAR*D’s actual measures of treatment success and failure were significantly worse than predicted. As Barbui et al noted, antidepressant study dropout rates provide a ‘hard measure of treatment effectiveness and acceptability’ (Barbui et al, 12 p296) and STAR*D’s dropout rate was 2.6 times greater than predicted.

   What are the treatment remission, response and extent of improvement

   bmjopen.bmj.com/content/13/7/e063095

   See all results for this question

   Do Star*D participants have depression?

   • The participants in STAR*D had moderate to severe depressive symptoms, with 75 percent having two or more episodes of depression in their lifetime and 25 percent reporting that their current episode of depression had continued for at least two years.

   Questions and Answers about the NIMH Sequenced Treatment Alternati…

   www.nimh.nih.gov/funding/clinical-research/practical/stard/backgroundstudy

   See all results for this question

   Does Star*D exclude depressed patients with bipolar disorder?

   • after four rounds, 70%. While STAR*D excluded depressed patients with bipolar disorder, a depressive episode in a patient with bipolar disorder can be difficult to distinguish from a depressive episode in a patient with major depressive dis-order. Primary care physicians need to consid-

   The STAR*D study: Treating depression in the real world

   www.ccjm.org/content/ccjom/75/1/57.full.pdf

   See all results for this question

   How does STAR*d help patients with citalopram failure?

   • For those patients who failed to gain an adequate response from citalopram, STAR*D allowed them to select acceptable treatment options for randomisation in levels 2 to 4 ‘to empower patients, strengthen the therapeutic alliance, optimize treatment adherence, and improve outcome’ (Fava et al, 20 p483).

   What are the treatment remission, response and extent of improvement

   bmjopen.bmj.com/content/13/7/e063095

   See all results for this question

   How did star*D work?

   • STAR*D aimed for the first time to provide solid scientific evidence regarding which next treatment steps are best for treatment-resistant depression. The results should produce clinical, administrative and economic benefits. 5. How did the researchers measure how well the medications worked? A.

   Questions and Answers about the NIMH Sequenced Treatment Alternati…

   www.nimh.nih.gov/funding/clinical-research/practical/stard/backgroundstudy

   See all results for this question

   Are Star*D treatments safe?

   • A. STAR*D treatments were selected with attention to what practitioners commonly use to treat clinical depression. The treatments selected were among the safest, easiest to take, and most frequently used. There were no placebo treatments used in this study.

   Questions and Answers about the NIMH Sequenced Treatment Alternati…

   www.nimh.nih.gov/funding/clinical-research/practical/stard/backgroundstudy

   See all results for this question

3. bmjopen.bmj.com › content › 13What are the treatment remission, response and extent of ...

   bmjopen.bmj.com › content › 13

   • Cached

   Interventions STAR*D evaluated the relative effectiveness of 13 antidepressants therapies in treatment levels 2–4 for depressed patients who failed to gain adequate benefit from their level 1 medication trial.

   • Download Powerpoint

     Patient flowchart. *In level 2, 580 patients were randomised...

4. www.bmj.com › content › 386New and emerging treatments for major depressive disorder

   www.bmj.com › content › 386

   • Cached

   This narrative review will focus on novel and emerging treatments for MDD (at any stage of the treatment cycle, from initial episode through to failure to respond to treatment) and their effectiveness, safety, and applicability in real world settings.

5. psychiatryonline.org › doi › 10What Did STAR*D Teach Us? Results From a Large-Scale ...

   psychiatryonline.org › doi › 10

   Nov 1, 2009 · To address these knowledge deficits, the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study, a large-scale clinical trial funded by the National Institutes of Health, aimed to develop and evaluate feasible treatment strategies to improve clinical outcomes for more representative, "real-world" outpatients with one or more ...

6. www.nimh.nih.gov › practical › stardSequenced Treatment Alternatives to Relieve Depression (STAR ...

   www.nimh.nih.gov › practical › stard

   • Cached

   Feb 25, 2008 · The NIMH-funded Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study was conducted to determine the effectiveness of different treatments for people with major depression who have not responded to initial treatment with an antidepressant.

7. www.ccjm.org › content › ccjomThe STAR*D study: Treating depression in the real world

   www.ccjm.org › content › ccjom

   The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study evaluated feasible treatment strategies to improve clinical outcomes for real-world patients with treatment-resistant depression.Although the study found no clear-cut “winner,” it does provide guidance on how to start therapy and how to proceed if initial treatment fails.

   • Author: Bradley Neil Gaynes, A. John Rush, Madhukar H. Trivedi, Stephen R. Wisniewski, Donald C Spencer, Mau...

   • Publish Year: 2008

8. www.nimh.nih.gov › practical › stardQuestions and Answers about the NIMH Sequenced Treatment ...

   www.nimh.nih.gov › practical › stard

   • Cached

   STAR*D aimed for the first time to provide solid scientific evidence regarding which next treatment steps are best for treatment-resistant depression. The results should produce clinical, administrative and economic benefits.

9. psychiatryonline.org › doi › pdfD What Did STAR D Teach Us? Results From a Large-Scale ...

   psychiatryonline.org › doi › pdf

   The authors provide an overview of the Sequenced Treatment Alterna-tives to Relieve Depression (STAR∗D) study (www.star-d.org), a large-scale practical clinical trial to determine which of several treatments are the most effective “next-steps” for patients with major depressive disorder whose symptoms do not remit or who cannot tolerate ...