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Jun 4, 2019 · In this Review, we explore the contributions of chromosome structure and nucleoid organization to cell cycle regulation, detail the cellular processes involved in the initiation of DNA...
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May 1, 2007 · In bacteria, the initiator DnaA cooperatively oligomerizes at the site of replication fork formation to direct melting of DNA duplex strands and loading of the replicative helicase DnaB.
- Melissa L. Mott, James M. Berger
- 2007
In this short film, Matt and Frank share how they devised the groundbreaking experiment that proved semiconservative DNA replication, what it was like to see the results for the first time, and how it felt to be at the forefront of molecular biology research in the 1950s.
- 22 min
In this short film, Matt and Frank share how they devised the groundbreaking experiment that proved semiconservative DNA replication, what it was like to see the results for the first time, and how it felt to be at the forefront of molecular biology research in the 1950s.
From doing studies with bacteria, and more particularly E. coli it could be determined that DNA can transmit hereditary information as well as self replicate. Use radioisotopic labels in DNA which would increase density and cause distinguishing features to be recognized
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Jan 4, 2024 · DNA replication initiation in bacteria starts with replication initiation proteins binding with the specific motifs within a well-defined origin region (Wolanski et al., 2014; Leonard and Grimwade, 2015), typically near the DUE region, where double-stranded DNA (dsDNA) melts (Rajewska et al., 2012).
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Introduction. DNA mismatch repair (MMR) is a highly conserved DNA repair system (Table 1) that greatly contributes to maintain genome stability through the correction of mismatched base pairs. The major source of mismatched base pairs is replication error, although it can arise also from other biological processes [1].