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Dec 31, 2018 · We found that replication preferentially initiates at the transcription start site of genes occupied by high levels of RNA polymerase II, and terminates at their polyadenylation sites, thereby...
- Supplementary Fig 1 Reproducibility of TSS Data Across Replicate Datasets
We would like to show you a description here but the site...
- Supplementary Fig 2 The Effect of Gene Length on TSS-proximal Origin Firing Efficiency is Not Solely a Result of Passive Replication
We would like to show you a description here but the site...
- Supplementary Fig 1 Reproducibility of TSS Data Across Replicate Datasets
Apr 27, 2024 · A comprehensive dataset to align DNA breaks to the linear movement of DNA replication and transcription in mouse neural progenitor cells. RDCs have been mapped across all chromosomes in mouse...
Apr 3, 2013 · This Review highlights the strategies used by prokaryotic and eukaryotic cells to minimize the consequences of collisions between replication forks and transcription complexes to effect...
- Anne Helmrich, Monica Ballarino, Monica Ballarino, Evgeny Nudler, Laszlo Tora
- 2013
Aug 30, 2020 · Here, we describe in detail how gene transcription influences DNA replication that leads to genome instability in normal and pathological conditions, and in the contribution to human diseases.
- Stefano Gnan, Stefano Gnan, Yaqun Liu, Yaqun Liu, Manuela Spagnuolo, Manuela Spagnuolo, Chun-Long Ch...
- 2020
Chapter 1: Why study chromosomes? 1. 1.1 Early studies of chromosomes, 1. 1.2 The origin of genetics, and the chromosome theory of inheritance, 1. 1.3 The chemical nature of genes and chromosomes, 2. 1.4 The position of chromosomes in an age of molecular biology, 3 Website, 4. Chapter 2: Mitosis, meiosis and the cell cycle, 5.
DNA packaging, by proteins, regulates gene expression was growing at a truly terrifying rate, as it continues to do. The subject has seen something of an infor-mation explosion. Practitioners in many different areas of science and medicine have discovered that the DNA–protein complex packed into the nucleus of the
People also ask
Do replication forks meet a transcription-elongation complex?
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How does DNA replication work?
Do DNA replication origins fire near the initiation site of highly transcribed genes?
What happens if replication-fork progression is slowed in human cells?
DNA replication takes place at a Y-shaped structure called a replication fork. A self-correcting DNA polymerase enzyme catalyzes nucleotide polymerization in a 5′-to-3′ direction, copying a DNA template strand with remarkable fidelity.
