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  1. Oct 17, 2021 · The NICE Review of gonadotropin-releasing hormone analogues (GnRHa), medications that block the production of the sex hormones testosterone and estrogen and are used to treat gender dysphoria in adolescents, was published in March 2021. The review included nine observational studies published no later than October 14, 2020: five retrospective studies, three prospective longitudinal studies ...

  2. clinical effectiveness, safety and cost-effectiveness of gonadotrophin releasing hormone (GnRH) analogues for children and adolescents aged 18 years or under with gender dysphoria. The document was prepared by NICE in October 2020. The content of this evidence review was up to date on 14 October 2020. See summaries of

  3. Apr 1, 2021 · Puberty blockers, known scientifically as gonadotrophin-releasing hormone (GnRH) analogues, are prescribed to some young people with gender dysphoria - distress caused by a discrepancy between a ...

  4. Mar 31, 2021 · In 2020, the UK National Institute for Health and Care Excellence (NICE) undertook two systematic evidence reviews of the use of GnRH agonists (also known as "puberty blockers") and cross-sex hormones as treatments for gender dysphoric patients <18 years old. These reviews were commissioned by NHS England, as part of a review of gender dysphoria healthcare led by Dr Hilary Cass OBE.

  5. The evidence reviews were published in March 2021. Unfortunately, the available evidence was not deemed strong enough to form the basis of a policy position. National Institute for Health and Care Excellence (2020). Evidence Review: Gonadotrophin Releasing Hormone Analogues for Children and Adolescents with Gender Dysphoria.

  6. MS & WHC’s 2020 recommendations on hormone replacement therapy in menopausal womenThe British Menopause Society (. MS) is the specialist authority for menopause and post reproductive health in the UK. The BMS educates, informs and guides healthcare professionals, working in both. primary and secondary care, on menopause and all aspects of ...

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  8. Nov 27, 2021 · A systematic review by Stute et al. (2016) assessed the impact of micronized progesterone on the endometrium. Forty studies were included in the systematic review and it concluded that oral micronized progesterone provides endometrial protection if applied sequentially for 12–14 days/month in a dose of 200 mg/day for up to five years. 18

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