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Compared with women, men usually have more muscle and less body fat. Hormone therapy can cause a decrease in muscle tissue and an increase in body fat. This can change the way your body looks and how physically strong you feel. Some men also experience muscle aches or joint pain while they’re on hormone therapy.
Side effects will usually last for as long as you’re on hormone therapy. If you stop using it, the side effects should improve as your testosterone levels start to rise again. Your side effects won’t stop straight away – it may take several months or years. For some men, the side effects may never go away completely. The risk of getting ...
Androgens (male sex hormones) are a class of hormones that control the development and maintenance of male characteristics. The most abundant androgens in men are testosterone and dihydrotestosterone (DHT). Androgens are required for normal growth and function of the prostate, a gland in the male reproductive system that helps make semen.
- Hormones are substances that are made by glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or orga...
- Early in their development, prostate cancers need androgens to grow. Hormone therapies, which are treatments that decrease androgen levels or block...
- Hormone therapy for prostate cancer can block the production or use of androgens ( 4 ). Currently available treatments can do so in several ways:...
- Hormone therapy may be used in several ways to treat hormone-sensitive prostate cancer, including: Early-stage prostate cancer with an intermediate...
- Doctors cannot predict how long hormone therapy will be effective in suppressing the growth of any individual man’s prostate cancer. Therefore, men...
- Treatments for castration-resistant prostate cancer include: Complete androgen blockade —that is, androgen receptor blockers ( flutamide , bicaluta...
- Researchers have investigated whether a technique called intermittent androgen deprivation can delay the development of hormone resistance. With in...
- Because androgens affect many other organs besides the prostate, ADT can have a wide range of side effects ( 4 , 27 ), including: loss of interest...
- Men who lose bone mass during long-term hormone therapy may be prescribed drugs to slow or reverse this loss. The drugs zoledronic acid (Zometa) a...
Hormonal therapies reduce the amount of testosterone in the body, or stop it reaching the prostate cancer cells. Testosterone is important for: sex drive (libido) getting an erection. facial and body hair. muscle development and bone strength. Hormonal therapies are drugs that can be given as injections or as tablets.
- Erection difficulties is called erectile dysfunction (ED). This usually improves after you stop hormonal therapy, depending on how long you take it...
- These may reduce as your body adjusts to hormonal treatment. They usually gradually improve after treatment finishes. Talk to your doctor or nurse...
- Feeling tired is a very common side effect of hormonal therapy. Regular physical activity can help reduce tiredness. Hot flushes may make sleeping...
- Talking about cancer to a family member, close friend or counsellor about how you feel may help with changes in your mood.
- Changes in memory and concentration may be caused by the hormone therapy, or because of tiredness or feeling anxious.
- You may gain weight (especially around the middle) and lose muscle strength. Eating well and keeping active can help manage this.
- This is more common if you have flutamide or and bicalutamide over a longer period. Some people have low-dose radiotherapy to their chest before tr...
- The risk of this is increased with long-term hormonal treatment. You may have a bone density scan to check your bones before you start treatment. R...
- Not smoking, eating well and keeping active can help reduce these risks.
What are the disadvantages of having hormone therapy? • It can cause side effects that can have an impact on your day to day life. Possible side effects are discussed later in this leaflet. • Hormone therapy alone will not cure prostate cancer. It may keep the cancer under control for an unknown period of time.
Aug 26, 2021 · The primary systemic treatment for prostate cancer, androgen deprivation therapy (ADT), lowers testosterone and causes side effects related to low testosterone. Although most men may experience only a few of these symptoms, the list of potential effects of testosterone loss is long: hot flashes, decreased sexual desire, loss of bone density and ...
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Oct 20, 2023 · There are 3 types of hormonal therapies for prostate cancer. They may be used alone or together. Luteinizing hormone-releasing hormone (LHRH) agonists block the signal from your pituitary gland that tells your testicles to make testosterone. Leuprolide (Lupron®) and goserelin (Zoladex®) are LHRH agonists.
