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Neuronal communication is therefore envisioned as the means of causing neurons to fire action potentials. A simplistic view is that such communication is the job of neurotransmission. However, neuromodulation plays just as direct a role in communicating such information.
How Neurons Communicate – Introduction to Psychology. Learning Objectives. Describe how neurons communicate with each other. Explain how drugs act as agonists or antagonists for a given neurotransmitter system.
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.
Conceptualization of neuronal populations as parts of a communication system offers a basis for understanding how brain regions interact. A clear framework of neuronal interactions, both nearby and distant, is necessary for the development of therapeutic interventions for many neurological disorders.
May 26, 2021 · Neuromodulators trigger second messenger cascades that affect neural circuits in two broad ways: (1) changing the excitability or temporal pattern of neuron activity and (2) altering the strength of synaptic connections between neurons (Marder and Bucher 2001; Dickinson 2006).
- Charlotte L Barkan, Elizabeth C Leininger, Erik Zornik
- 2021
Neuronal communication is made possible by the neuron’s specialized structures, like the soma, dendrites, axons, terminal buttons, and synaptic vesicles. Neuronal communication is an electrochemical event. The dendrites contain receptors for neurotransmitters released by nearby neurons.
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What is Neuromodulation?
In this section, we consider the conduction of communication within a neuron and how this signal is transmitted to the next neuron. There are two stages of this electrochemical action in neurons. The first stage is the electrical conduction of dendritic input to the initiation of an action potential within a neuron.
