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Rogers and colleagues review the advances in developing implantable devices to control neural activity, summarizing the major modes of modulation, sensing, and operation. They lay out a path forward and chart our progress miniaturized, wirelessly powered, stretchable, and bioresorbable designs.
- Sang Min Won, Enming Song, Enming Song, Jonathan T. Reeder, John A. Rogers
- 2020
Jan 1, 2022 · Technology Stack for a Neuromodulation Device. The system interacts with the nervous system through material interfaces for sensing physiologic signals as well as stimulation. The sensors can include direct measurements of electrical activity or surrogates such as inertial signals.
- Tim Denison, Martha J. Morrell
- Neurology. 2022 Jan 11; 98(2): 65-72.
- 10.1212/WNL.0000000000013061
- 2022/01/01
Jul 14, 2014 · This paper reviews the state-of-the-art in ENS as well as alternative neuromodulation techniques—presenting the operational concepts, technical implementation and limitations—in order to inform system design choices.
Mar 3, 2022 · These examples illustrate the ability of neuromodulation therapies to adjust stimulation dynamically. Responsive neuromodulation is also an area of active research and development. Clinical trials are underway to adapt DBS systems to respond to changes in electrophysiological signals.
Jan 4, 2017 · Nature Reviews Materials - Understanding the dynamics and architecture of the nervous system requires tools for recording and modulating the activity of billions of neurons. This Review...
Neuromodulation is defined by the International Neuromodulation Society as a field of science, medicine, and bioengineering that encompasses implantable and nonimplantable technologies, electrical or chemical, that have an impact on neural interfaces to improve life for humanity.
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Aug 16, 2023 · We first present a consensus definition of neuromodulation. We then describe a classification scheme based on the 1) intended use (the site of modulation and its indications) and 2) physical properties (waveforms and dose) of a neuromodulation therapy.