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  1. Our discussion covers a breadth of modalities in neuromodulation, from electrical, thermal, and optical to pharmacological and multimodal combinations of these, in tissue-compliant and wireless platforms with demonstrated utility in animal model studies and clear promise in clinical translation.

    • Sang Min Won, Enming Song, Enming Song, Jonathan T. Reeder, John A. Rogers
    • 2020
  2. Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.

  3. Micro- and nanostructured electrodes permit intracellular recordings and modulation of sub-threshold events at finer temporal resolution and longer duration than conventional patch-clamp electrophysiology.

    • Ritchie Chen, Andres Canales, Polina Anikeeva
    • 10.1038/natrevmats.2016.93
    • 2017
    • 2017/02
  4. May 26, 2021 · Neuromodulators are a diverse set of intercellular signaling molecules with conserved cellular mechanisms across species (e.g., Katz and Lillvis 2014; Kamhi et al. 2017).

  5. Nov 17, 2022 · Magnetic modulation of cellular function relies on transducers capable of converting magnetic fields into signals perceived by biological receptors, referred to as mediators (Fig. 1). Cells can...

  6. May 11, 2021 · Here, we present a bacteria-animal symbiont system in which engineered bacteria recognize external signals and modulate animal gene expression, twitching phenotype, and fat metabolism through...

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  8. Jun 1, 2018 · This will open new possibilities for employing synthetic biology to advance personalized medicine by converting cells into living therapeutics to combat hitherto intractable diseases.

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