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1. www.nature.com › articles › s41370/023/00635-wReconstructing individual-level exposures in cohort analyses ...

   www.nature.com › articles › s41370/023/00635-w

   Jan 8, 2024 · The definition of the exposure summaries first requires assumptions on the temporal dependency between exposure and outcomes, determined by underlying biological mechanisms.

2. besjournals.onlinelibrary.wiley.com › doi › fullExposure and susceptibility: The Twin Pillars of infection

   besjournals.onlinelibrary.wiley.com › doi › full

   May 3, 2022 · We provide a framework for conceptualising exposure–susceptibility interactions, where they obscure, confound, induce or counteract one another, providing some well-known examples for each complicating mechanism.

   • Author: Amy R. Sweeny, Gregory F. Albery
   • Published: 03 May 2022

   • Cited By: 3
   • Volume: 36, Issue7

3. bmcmedresmethodol.biomedcentral.com › articles › 10A review of the reporting and handling of missing data in ...

   bmcmedresmethodol.biomedcentral.com › articles › 10

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   Jul 11, 2012 · Retaining participants in cohort studies with multiple follow-up waves is difficult. Commonly, researchers are faced with the problem of missing data, which may introduce biased results as well as a loss of statistical power and precision.

   • Author: Amalia Karahalios, Amalia Karahalios, Laura Baglietto, Laura Baglietto, John B Carlin, Dallas R Engl...

   • Publish Year: 2012

4. academic.oup.com › aje › articleThings Don’t Always Go as Expected: The Example of ...

   academic.oup.com › aje › article

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   Feb 21, 2020 · The scenario in Table 1, classification D, provides a hypothetical example of study data that yield an overestimate despite nondifferential misclassification of exposure in probability. But, a single example does not provide information regarding how commonly such results may occur or why.

   • Author: Brian W Whitcomb, Ashley I Naimi

   • Publish Year: 2020

5. www.ncbi.nlm.nih.gov › books › NBK126191Exposure Definition and Measurement - Developing a Protocol ...

   www.ncbi.nlm.nih.gov › books › NBK126191

   A study's conceptual basis should serve as the foundation for developing an operational definition of exposure. That is, if the objective of the study is to examine the impact of chronic use of a new medication on patient outcomes, then the measurement of exposure should match this goal.

   • Author: Todd A Lee, A Simon Pickard
   • Published: 2013/01

   • Publish Year: 2013

6. academic.oup.com › genetics › articleEpigenetic Inheritance and the Missing Heritability Problem

   academic.oup.com › genetics › article

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   Jul 1, 2009 · Inherited epigenetic changes have been proposed as an explanation for the “missing heritability,” meaning inherited causes of risk of complex genetic diseases that have not yet been identified in genomewide association studies (GWAS) (Maher 2008; McCarthy and Hirschhorn 2008).

7. People also ask

   Are there missing data for exposure measures?

   • We have conducted a review of publications from cohort studies in order to document the reporting of missing data for exposure measures and to describe the statistical methods used to account for the missing data. A systematic search of English language papers published from January 2000 to December 2009 was carried out in PubMed.

   A review of the reporting and handling of missing data in cohort

   bmcmedresmethodol.biomedcentral.com/articles/10.1186/1471-2288-12-96

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   What are exposure summaries?

   • The definition of the exposure summaries first requires assumptions on the temporal dependency between exposure and outcomes, determined by underlying biological mechanisms. Two intertwined aspects are particularly relevant: the timescale of the association and the related exposure window.

   Reconstructing individual-level exposures in cohort analyses of environ…

   www.nature.com/articles/s41370-023-00635-w

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   What is exposure in epidemiology?

   • In epidemiology, the term “exposure” can be broadly applied to any factor that may be associated with an outcome of interest. When using observational data sources, researchers often rely on readily available (existing) data elements to identify whether individuals have been exposed to a factor of interest.

   Chapter 4 Exposure Definition and Measurement - National Center for

   www.ncbi.nlm.nih.gov/books/NBK126191/

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   Is exposure misclassification related to the outcome?

   • In particular, the connection between the likelihood of exposure misclassification being related to the outcome and how misclassification occurs in a given data set and how bias from misclassification is related to error in a given study are prone to misperceptions.

   Things Don’t Always Go as Expected: The Example of Nondifferential

   academic.oup.com/aje/article/189/5/365/5742066

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   What should a researcher know about exposure?

   • Investigators should understand the benefits and limitations associated with the data source being used, and should ensure that the exposure can be measured with sufficient precision to answer the research question of interest.

   Chapter 4 Exposure Definition and Measurement - National Center for

   www.ncbi.nlm.nih.gov/books/NBK126191/

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   What is the exposome?

   • Vrijheid M. The exposome: a new paradigm to study the impact of environment on health. Thorax. 2014;69:876–8. This research has been conducted using the UK Biobank Resource under application number 56431. This work was part of a PhD project supported by the Nagasaki University WISE Programme.

   Reconstructing individual-level exposures in cohort analyses of environ…

   www.nature.com/articles/s41370-023-00635-w

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8. www.nature.com › articles › s43588/021/00086-zUndisclosed, unmet and neglected challenges in multi-omics ...

   www.nature.com › articles › s43588/021/00086-z

   Jun 21, 2021 · Missing values can be caused by features failing to be measured in some of the samples, a frequent scenario in proteomics and metabolomics data, or by detection difficulties inherent to the ...