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Biological fluids (i.e., blood, serum, plasma) and excreta (i.e., saliva, feces, urine) collected with minimally invasive methods are ideal for sampling in clinical and epidemiological investigations aimed at understanding how the environment perturbs molecular, microbial, and biochemical pathways.
- Kristine K. Dennis, Scott S. Auerbach, David M. Balshaw, Yuxia Cui, Margaret Daniele Fallin, Martyn ...
- 2016
May 3, 2022 · We provide a framework for conceptualising exposure–susceptibility interactions, where they obscure, confound, induce or counteract one another, providing some well-known examples for each complicating mechanism.
- Amy R. Sweeny, Gregory F. Albery
- 03 May 2022
- 3
- 36, Issue7
Apr 29, 2024 · What has been missing is a systematic approach analogous to genome-wide association studies, which have identified dozens of genes involved in Alzheimer’s disease, Parkinson’s disease and other...
The exposome is a concept used to describe environmental exposures that an individual encounters throughout life, and how these exposures impact biology and health. It encompasses both external and internal factors, including chemical, physical, biological, and social factors that may influence human health.
Exposure Biology. A better understanding of the complex nature of how a person’s environment contributes to their health requires sustained development of technology to measure exposures. This includes better biomarkers, new sensors and monitors, and remote detection of exposures. NIEHS-funded scientists are:
Jan 24, 2020 · The “exposome” concept strives to capture the diversity and range of exposures to synthetic chemicals, dietary constituents, psychosocial stressors, and physical factors, as well as their corresponding biological responses.
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What is an exposome & why is it important?
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Is biological impact outside the concept of the exposome?
May 1, 2014 · Exposures are variables that we wish to evaluate for their potential relation with adverse health outcomes or variables that denote groups at particularly higher risk for adverse health. For example, we consider biological sex an exposure that may be associated with adverse health outcomes.
