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  1. Familial Mediterranean fever is an inherited autoinflammatory syndrome characterised by recurrent short episodes of high fever associated with abdominal pain, inflammation of joints and other body sites and skin rash. If untreated, amyloidosis commonly develops and may have a fatal outcome.

  2. Nov 11, 2021 · Signs and symptoms of familial Mediterranean fever usually begin during childhood. They occur in bouts called attacks that last 1-3 days. Arthritic attacks may last for weeks or months. Signs and symptoms of FMF attacks vary, but can include: Fever; Abdominal pain; Chest pain, which can make it hard to breathe deeply

  3. Jul 16, 2023 · Overview. Symptoms. Complications. Genetics and Inheritance. Risk Factors. Familial Mediterranean fever (FMF) is a rare genetic disorder that is primarily seen in some ethnic populations. It is also sometimes called familial paroxysmal polyserositis or recurrent polyserositis.

  4. 5. pre-attack symptoms, occurring 12 to 24 hours before any FMF attacks, usually including discomfort, abnormal taste sensation, dizziness, increased appetite, irritability, etc. Type 2 FMF is characterized by amyloidosis as the first clinical manifestation of the disease, in otherwise asymptomatic people.

  5. Sep 30, 2010 · Familial Mediterranean fever is primarily a genetic disease due to Mendelian-recessive inheritance of Mediterranean fever gene mutations. Occurs mainly in people of Mediterranean ancestry, especially from Arab countries, Turkey, Israel, and Armenia. Characterised by recurrent attacks of fever and...

  6. Apr 25, 2024 · Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease characterized by recurrent episodes (attacks) of fever and acute inflammation of the membranes lining the abdomen, joints and lungs.

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  8. Jul 26, 2023 · What are the signs and symptoms of familial Mediterranean fever? Familial Mediterranean fever usually presents with periodic fevers and severe chest, abdominal, or joint pain associated with the serositis, followed by periods where individuals remain symptom-free.

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