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Apr 9, 2005 · C2 is the final concentration of the diluted solution. V2 is the final volume of the diluted solution. This is the volume that results after V1 from the stock solution has been diluted with diluent to achieve a total diluted volume of V2. An alternative and commonly-used notation for this equation is M1V1 = M2V2, where M is used in place of C.
- Calculators
Dilution Calculator - Mass per Volume (e.g., pg/mL, μg/μL,...
- Calculators
Jan 20, 2018 · As another example, if 100 mL of a stock solution is diluted with solvent/diluent to a total, final volume of 1000 mL, the resulting dilution factor is 10. It can also be said that the stock solution was diluted 10-fold. Therefore, a 10-fold dilution is the same as a dilution factor of 10.
- Medicine X contains 2g of the solid ingredient within 500g of product. A further 250g of vehicle is added to the product. Find the concentration of the diluted mixture as a percentage strength, a ratio strength and an amount strength (in mg/g)?.
- 100mL of a 1 in 50 w/v solution is diluted to 1000mL. Find the concentration of the diluted product as a percentage strength, a ratio strength and an amount strength expressed as mg/mL.
- What volume of a 1 in 400 v/v solution is needed to produce 5L of a 1 in 2000 v/v solution? Let y mL be the volume of 1 in 400 solution needed.
- What volume of a 40% v/v solution must be used to produce 500mL of 5% v/v solution? Let y mL equal the volume of 40% v/v solution needed. There is also x mL of ingredient in 500mL of the 5% v/v solution.
- Introduction
- Basic Principles
- Dose by Weight
- Dosing in Renal Impairment
- Infusion Doses and Rate
- Opioid Conversion
- Concentrations
- Paediatric Dosing
- References
Drug calculation skills are an important part of prescribing, as calculation errors may lead to significant patient harm. This is particularly important when prescribing for the elderly and paediatric populations, as they are more vulnerable to medication-related harm. Frailty and reduced renal function are commonly seen in the elderly population. ...
When carrying out a drug calculation, there are some basic principlesto keep in mind: 1. Convert all dose units to the same units to avoid confusion 2. Percentage concentrations are expressed as weight/volume (w/v) = 1 g in 100 ml; volume/volume (v/v) = 1 ml in 100 ml; weight/weight (w/w) = 1 g in 100 g; volume/weight (v/w) = 1 ml in 100 g 3. For c...
Actual body weight
A 50-year-old patient who weighs 105 kg with type 2 diabetes is to be switched to insulin pens. You decide to prescribe a starting dose of 0.2 units/kg. Calculate the insulin dose in units for this patient.
Ideal body weight
You are the FY1 on the respiratory ward. You have been asked to prescribe intravenous aminophylline for a 53-year-old man who weighs 89 kg and is 165 cm. He was admitted with acute severe asthma and was not previously on theophylline. He is allergic to penicillin, does not smoke and has no co-morbidities. The consultant has requested an initial loading dose of 6mg/kg and a subsequent maintenance dose of 0.7 mg/kg/hour. Calculate the loading dose and maintenance dose of intravenous aminophylli...
Adjusted body weight
In clinical practice, the adjusted body weight may be used in obese patients who are >20% of their ideal body weightto prevent overdosing in these patients. This only applies to some medications with poor distribution in adipose tissues, such as aminoglycosides (e.g. gentamicin and amikacin) and varies depending on local guidelines. Resources 1. Adjusted body weight calculator
A 72-year-old man has been admitted with a pulmonary embolism. He weighs 70kg. According to local guidelines, subcutaneous enoxaparin is the first-line treatment for pulmonary embolism. His serum creatinine level is 220 micromol/L. What dose of enoxaparin should be prescribed for this patient? Calculate the patient’s renal function using the Cockcr...
During your rotation in the emergency department, a 24-year-old woman who weighs 60 kg was brought in by ambulance following a seizure. Whilst in ED, she develops prolonged seizures and status epilepticus. The consultant has decided to commence intravenous phenytoin with a loading dose of 1000 mg, which is to be diluted in 100 ml of normal saline. ...
A patient requires switching from oral morphine to fentanyl patches as they are now nil by mouth. The patient takes MST Continus 30 mg twice daily and Oramorph 10mg/5ml, 5 ml four times a day for breakthrough pain. Using the information provided, what is the recommended strength of fentanyl patch in micrograms/hour for this patient? Note: Round dow...
A 40-year-old woman, who weighs 50 kg, is hypokalaemic. She requires a potassium infusion of 500 ml of 0.18% w/v solution. You have 15% potassium chloride concentrate in stock. How much 15% potassium chloride concentrate (in ml) is required for this infusion?
Dose by age
A 6-year-old child presents with fever, sore throat and a “sandpaper” rash which started from the chest and spread towards the abdomen. You have diagnosed the patient with scarlet fever and decided to prescribe phenoxymethylpenicillin for this patient. How many bottles of phenoxymethylpenicillin should you prescribe for this patient? Available pack sizes: 1. 125 mg/5ml 100 ml 2. 250 mg/5ml 100 ml Resources: 1. BNF: Phenoxymethylpenicillin
Dose by weight
You were required to prescribe nitrofurantoin for a urinary tract infection in a 10-month-old child who weighs 9.5 kg. Nitrofurantoin suspension comes in 25mg/5ml. Calculate the dose in ml required for this patient. Resources 1. BNF: Nitrofurantoin
Dose by body surface area
A 5-month-old child was admitted with encephalitis following an episode of chickenpox. He requires aciclovir 500mg/m2every 8 hours for 10 days. The child has a height of 66 cm and weighs 7 kg. Calculate the dose of aciclovir for this patient.
Electronic Medicines Compendium. Summary of Product Characteristics. Available from: [LINK]British National Formulary. Available from: [LINK]Aug 2, 2013 · Mass per volume (mass / volume) concentration equation. C is the desired concentration of the final solution with the concentration unit expressed in units of mass per volume of solution (e.g., mg/mL). m is the mass (i.e., weight) of solute that must be dissolved in volume V of solution to make the desired solution concentration (C).
Jul 29, 2024 · We must administer 0.1 mg per pound of body weight to a 20 lb child. To calculate how much of the drug should be administered: Dose = Weight × Dosage. Dose = 20 lbs × (0.1 mg / 1 lbs) = 2 mg. To calculate the dose of the syrup: Liquid dose = Dose/Concentration. Liquid dose = 2 mg/(1 mg / 2 mL) = 4 mL.
People also ask
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How do you calculate weight/volume percentage concentration?
In weight per volume terms (mass per volume terms), this means a percentage concentration tells us the parts of solute by mass per 100 parts by volume of solution. In SI units, w/v% (m/v%) concentration would be given in kg/100 L, but these units are far too large to be useful to Chemists in the lab, grams and milliltres are more convenient units for us.
