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The fentanyl equivalence table below should not be used for opioid naïve patients or those stable on immediate release morphine for several weeks. Fentanyl equivalences in this table are for patients on well-tolerated opioid therapy for long periods. Conversion ratios vary and these figures are a guide
Morphine. Conversions are complex. 1.3mg oral hydromorphone is equivalent to 10mg oral morphine. Please seek advice. Depending on age, comorbidities and prior side effects, consider reducing the dose of the new opioid by up to 33-50% when converting between strong opioids.
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5mcg/hr. 10mcg/hr. 20mcg/hr. Morphine oral. 9-14mg per day. 18-28mg per day. 36-55mg per day. The manufacturer of Transtec® recommends starting with the lowest strength patch. However, if the patient was already taking ≥120mg morphine orally or equivalent, the 52.5mcg/hr strength is suggested as the initial dose.
OPIOID CONVERSION CHART JUNE 2020 Fentanyl patch mcg/hr Equivalent 24hr dose of oral morphine PRN dose of Oramorph required 12 30-45mg 5-10 mg 25 60-90mg 10-15mg 37 90-135mg 15-20mg 50 120-190mg 20-30mg 62 150-220mg 25-35mg 75 180-310mg 30-45mg doses >75mcg/hr: seek specialist advice atch Buprenorphine Patch mcg/hr Equivalent 24hr dose
Prescribe 4 hourly prn doses of subcutaneous (sc) morphine unless contraindicated. If 2 or more rescue/ prn doses are needed in 24 hours, start a syringe driver with appropriate opioid and continue patch(es). The opioid dose in the SD should equal the total prn doses given in the previous 24 hours up to a maximum of 50% of the existing regular ...
Converting po dihydrocodeine to po morphine. 30/500 co-dydramol given as 2 tablets QDS = 60mg dihydrocodeine x4 = 240mg in 24 hours. Table below, co-dydramol potency equivalence = 0.1Multiply 240mg x 0. 24mgTherefore, the approximate equivalent 2. Prescribe morphine MR 10mg BD 12 hours apart.
Opioid Conversion Tables . Ernest Dole , Pharm.D., BCPS , PhC, FASHP . Clinical Pharmacist , University of New Mexico Hospitals . Chronic Pain C onsultation & Treatment Center . Table 1: Pharmacokinetic Data for Oral Opioids . Starting Dose Onset Peak Duration Half life Codeine 30 - 60 mg q 4 hr 30 min 1.5 hr 6 hours 2-4 hr Morphine SA
