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  1. Antidepressant withdrawal from both sides of the desk. Update: A publication date has just been announced for our handbook on how to safely stop psychiatric drugs called the Maudsley Deprescribing Guidelines. It will be published in the UK and Europe on the 15th of February, 2024 as a paperback (already available as a kindle version) and in the ...

    • Academic Papers

      Joanna Moncrieff, Swapnil Gupta and Mark Horowitz. July 6,...

    • Media Articles

      An academic psychiatrist in training on how to stop...

    • Video and Audio

      Antidepressant Withdrawal and its Management – 55 minute...

    • Blog

      Response to criticism of our serotonin in depression paper....

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      If you are located in the states of California, Colorado,...

  2. Outro is the first service for safe, evidence-based antidepressant tapering, designed by expert clinicians and patients who’ve been there. Based in Dr. Mark Horowitz's leading research, Outro's tapering program combines neurobiology-based tapering, integrative approaches and virtual care to provide an accessible, personalized path off medication.

  3. Podcast; Turning the Tide on Overmedication: Dr. Mark Horowitz’s Approach to Deprescribing, Part 1 May 14, 2024 Dr. Mark Horowitz, a Clinical Research Fellow in Psychiatry from the UK and co-author of “The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs,” delves into the complexities of deprescribing psychiatric medications such as ...

  4. Jul 31, 2024 · Horowitz has written landmark deprescrib­ing guidelines for clinicians that include evidence-based advice on stopping antidepres­sant use. Titled the Maudsley Deprescrib­ing Guidelines, the instructio­ns were officially endorsed by the Royal Australian College of General Practition­ers (RACGP) on Wednesday amid growing concern about a lack of advice for doctors and patients.

  5. Antidepressant Withdrawal and its Management – 55 minute instructional video for doctors and patients.

  6. If you are located in the states of California, Colorado, Washington, or DC, and are looking for support in safely discontinuing an antidepressant medication, consider reaching out to the clinical team at Outro Health.

  7. Dr. Horowitz is a neuroscientist, a Clinical Research Fellow in Psychiatry at the National Health Service in England, and a world-leading researcher in psychiatric medication deprescribing. Mark co-wrote the Royal College of Psychiatrists' guidelines on antidepressant discontinuation, based on the p

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