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In vivo hMSCs are sources of trophic factors modulating the immune system and inducing intrinsic stem cells to repair damaged tissues. Currently, there are multiple clinical trials (CT) using hMSCs for therapeutic purposes in a large number of clinical settings.
- Stem cells: a comprehensive review of origins and emerging ...
Stem cells are types of cells that have unique ability to...
- Mesenchymal stem cells from biology to therapy - PMC
As therapeutics, mesenchymal stem cells or even just their...
- The bone marrow niche for haematopoietic stem cells - PubMed
Abstract. Niches are local tissue microenvironments that...
- Mesenchymal stem cells from biology to therapy - PubMed
As therapeutics, mesenchymal stem cells or even just their...
- Stem cells: a comprehensive review of origins and emerging ...
Aug 25, 2022 · Stem cells are types of cells that have unique ability to self-renew and to differentiate into more than one cell lineage. They are considered building blocks of tissues and organs. Over recent decades, they have been studied and utilized for repair and regenerative medicine.
Oct 10, 2021 · As therapeutics, mesenchymal stem cells or even just their secreted products may be used to regenerate tissue lost through injury or disease and suppress damaging immune reactions. However, these cells lack unique markers and are hard to identify and isolate as pure cell populations.
- David Kuntin, Paul Genever
- 2021/10/10
- 10.1042/ETLS20200303
Jan 15, 2014 · Haematopoietic stem cell (HSC) niches are present in diverse tissues throughout development, beginning in the aorta–gonad–mesonephros (AGM) region and the yolk sac, followed by the placenta,...
- Sean J. Morrison, David T. Scadden
- 2014
Jan 16, 2014 · Abstract. Niches are local tissue microenvironments that maintain and regulate stem cells. Haematopoiesis provides a model for understanding mammalian stem cells and their niches, but the haematopoietic stem cell (HSC) niche remains incompletely defined and beset by competing models.
- Sean J. Morrison, David T. Scadden
- 2014
We begin by discussing experimental advances in the generation and differentiation of pluripotent stem cells (PSCs), next moving to the maintenance of stem cells in different culture types, and finishing with a discussion of three-dimensional (3D) cell technology and future stem cell applications.
Oct 29, 2021 · As therapeutics, mesenchymal stem cells or even just their secreted products may be used to regenerate tissue lost through injury or disease and suppress damaging immune reactions. However, these cells lack unique markers and are hard to identify and isolate as pure cell populations.
Advances in all areas of stem cell biology and regenerative medicine. Stem Cells and Regenerative Medicine published with eLife Assessment and Public Reviews