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    • Genetic disorder

      • Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome.
      www.mayoclinic.org/diseases-conditions/down-syndrome/symptoms-causes/syc-20355977

      Down syndrome - Symptoms and causes - Mayo Clinic

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  3. www.nhs.uk › conditions › downs-syndromeDown's syndrome - NHS

    Down's syndrome is when you're born with an extra chromosome. You usually get an extra chromosome by chance, because of a change in the sperm or egg before you're born. This change does not happen because of anything anyone did before or during pregnancy. What it's like to have Down's syndrome.

  4. www.everydayhealth.com › down-syndrome › definitionThe Different Types of Down Syndrome - Everyday Health

    Nov 26, 2022 · Down syndrome is a genetic condition that causes a range of physical, behavioral, and cognitive symptoms. There are three types, and each person with Down syndrome has unique strengths and...

  5. www.mayoclinic.org › diseases-conditions › downDown syndrome - Symptoms and causes - Mayo Clinic

    • Overview
    • Symptoms
    • Causes
    • Risk Factors
    • Complications
    • Prevention

    Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome. Down syndrome varies in severity among individuals, causing lifelong intellectual disability and developmental delays. ...

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    Each person with Down syndrome is an individual — intellectual and developmental problems may be mild, moderate or severe. Some people are healthy while others have significant health problems such as serious heart defects. Children and adults with Down syndrome have distinct facial features. Though not all people with Down syndrome have the same f...

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    Human cells normally contain 23 pairs of chromosomes. One chromosome in each pair comes from your father, the other from your mother. Down syndrome results when abnormal cell division involving chromosome 21 occurs. These cell division abnormalities result in an extra partial or full chromosome 21. This extra genetic material is responsible for the...

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    Some parents have a greater risk of having a baby with Down syndrome. Risk factors include: 1. Advancing maternal age.A woman's chances of giving birth to a child with Down syndrome increase with age because older eggs have a greater risk of improper chromosome division. A woman's risk of conceiving a child with Down syndrome increases after 35 yea...

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    People with Down syndrome can have a variety of complications, some of which become more prominent as they get older. These complications can include: 1. Heart defects.About half the children with Down syndrome are born with some type of congenital heart defect. These heart problems can be life-threatening and may require surgery in early infancy. ...

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    There's no way to prevent Down syndrome. If you're at high risk of having a child with Down syndrome or you already have one child with Down syndrome, you may want to consult a genetic counselor before becoming pregnant. A genetic counselor can help you understand your chances of having a child with Down syndrome. He or she can also explain the pre...

    See full list on mayoclinic.org

  6. ndss.org › myths-truthsFacts, Myths, & Truths About Down Syndrome - NDSS

    • MYTH: Down syndrome is a rare disorder. TRUTH: Down syndrome is the most commonly occurring chromosomal condition. Approximately one in every 772 babies in the United States is born with Down syndrome, or around 5,100 births per year.
    • MYTH: Down syndrome is hereditary and runs in families. TRUTH: Translocation, a type of Down syndrome that accounts for 3 to 4% of all cases, is the only type of Down syndrome known to have a hereditary component.
    • MYTH: Most children with Down syndrome are born to older parents. TRUTH: Most children with Down syndrome are born to women younger than 35 years old simply because younger women have more children.
    • MYTH: Parents will not find community support in bringing up their child with Down syndrome.

  7. www.newcastle-hospitals.nhs.uk › downs-syndromeDown's Syndrome - Newcastle Hospitals NHS Foundation Trust

    Down’s syndrome or Trisomy 21 is a chromosomal disorder caused by the presence of all, or part of, an extra chromosome 21. Clinical Features. A neonate with Down’s syndrome usually shows marked hypotonia, small ears, up-slanting palpebral fissures, flat facial profile and brachycephaly.

  8. downsyndromeuk.co.uk › resources › what-is-down-syndromeWhat is Down syndrome? - Down Syndrome UK

    Down syndrome is... a naturally occurring genetic condition caused by an extra chromosome. Babies with Down syndrome are born in every country to parents of all ages, races, religions, and backgrounds.

  9. my.clevelandclinic.org › health › diseasesDown Syndrome: Symptoms & Causes - Cleveland Clinic

    Jan 31, 2023 · Down syndrome is a genetic condition where a person is born with an extra copy of chromosome 21. This means that they have a total of 47 chromosomes instead of 46. This can affect how their brain and body develop. People diagnosed with Down syndrome have happy and healthy lives with supportive care.

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