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Clinical Evidence for Aberrant Learning and Memory in Addiction. Despite the wealth of pre-clinical data favoring an aberrant learning and memory conception of addiction, there is a lack of clinical research exploring exactly how learning accrues to drug predicting stimuli in human subjects.
- Mary M. Torregrossa, Philip R. Corlett, Jane R. Taylor
- 2011
Everitt, Dickinson & Robbins (2001) argued that the aberrant engagement of pavlovian and instrumental learning mechanisms, due perhaps to the ability of drugs of abuse to increase dopamine release in parts of the limbic cortico-ventral striatal system, leads to enhanced learning about the actions and environmental, drug-associated
Sep 21, 2022 · The aberrant learning theory —this theory is based on the role of dopamine as a reward prediction error signal. Dopamine signals an error between the prediction of a reward and the actual...
Oct 10, 2008 · More specific evidence for incentive sensitization comes from studies designed to more directly assess drug-induced changes in the incentive salience attributed to reward-related stimuli, and to exclude alternative explanations for increases in reward-directed behaviour based on habit learning, etc. Stimuli acquire incentive properties by being ...
Nov 26, 2021 · For example, aberrant learning theory hypothesizes that, although once governed by action–outcome learning and so goal-directed, drug seeking and use in addiction has devolved into inflexible, stimulus–response learning, and so is independent of cognitive and motivational states such as beliefs and desires (Everitt & Robbins 2005; Lüscher ...
Aberrant-learning theories of addiction These theories propose that repeated exposure to addictive drugs heightens Pavlovian and instrumental responsiveness to drug-associated cues through...
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These include: (a) the traditional hedonic view that drug pleasure and subsequent unpleasant withdrawal symptoms are the chief causes of addiction; (b) the view that addiction is due to aberrant learning, especially the development of strong stimulus- response habits; (c) our incentive-sensitization view, which suggests that sensitization of a n...
