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  2. Dec 28, 2023 · The SHAMAL study has made a significant breakthrough in severe asthma treatment. It demonstrates that the biologic therapy benralizumab enables patients to significantly reduce or stop the use of high-dose inhaled steroids, which are known for serious side effects.

  3. Dec. 8, 2021 — In a late-stage clinical trial, the biologic agent dupilumab reduced the rate of severe asthma attacks and improved lung function and asthma control for children ages 6 to 11. The...

    • Overview
    • Purpose of asthma treatments
    • Treatment options
    • The future of severe asthma treatments
    • Takeaway

    New treatments for severe asthma may include biologics, surgical techniques, and leukotriene modifiers, among others. Researchers are still searching for new drugs to prevent and relieve asthma.

    Asthma is a disease that causes the airways to swell up and tighten, making it hard to catch your breath. Symptoms include:

    •wheezing

    •shortness of breath

    •chest tightness

    Symptoms can be more severe in some people and less severe in others. You might only have symptoms at certain times, like when you exercise. You could also have frequent asthma attacks that affect your quality of life.

    Asthma treatment involves a three-part strategy:

    •using long-term management medications to prevent symptoms before they start

    •using quick-relief medications to stop acute asthma attacks

    •avoiding triggers to reduce the number of attacks

    The main treatment for severe asthma is taking long-term management medications that help prevent asthma symptoms. These include:

    •inhaled corticosteroids

    •inhaled long-acting beta-agonists

    •inhaled long-acting anticholinergics

    •leukotriene modifiers

    •cromolyn sodium (Intal)

    Researchers are still searching for new drugs that will be able to prevent and relieve asthma symptoms. One drug that generated potential is Fevipiprant.

    While in development, this experimental drug reduced symptoms and airway inflammation in people with allergic asthma that inhaled corticosteroids could not, according to 2016 research.

    However, the company Novaris, which was developing Fevipiprant, decided to cease further development due to trials showing that the drug didn’t do much better than a placebo.

    Some research is focusing on how combining multiple existing medications can aid in managing asthma attacks.

    A 2021 review suggests adding long-acting muscarinic antagonist to inhaled corticosteroids and long-acting β2-agonists could lead to fewer severe asthma attacks and modest improvement in asthma management.

    Other studies are investigating the factors that play a role in asthma development, such as calcium-sensing receptor (CaSR). Identifying the triggers that set off asthma symptoms could one day enable researchers to stop those processes and prevent asthma before it starts.

    Asthma is a disease that causes the airways to swell up and tighten, making it hard to breathe. There is currently no cure for asthma, but there are treatment options that can help reduce its symptoms.

    If you have severe symptoms, you may require multiple treatment options for your asthma. Talk with your doctor about which options are best for you.

  4. May 3, 1999 · But asthma is not curable in the same way as, say, a bacterial pneumonia; it never entirely goes away. Also, no one cure would ever suffice. It is becoming increasingly clear that there many...

  5. Aug 12, 2022 · There is currently no cure for asthma; however, current treatments help to keep symptoms under control for most people. Now, new research may have found a way to treat asthma in the...

  6. Jul 18, 2024 · Asthma imposes a substantial health and economic burden on patients and their families and on the health care system. An assessment of the status of asthma in the US may lead to effective strategies to improve health and quality of life among people with asthma.

  7. Apr 4, 2024 · The new study, published today in Science, shows for the first time that many features of an asthma attack -- inflammation, mucus secretion, and damage to the airway barrier that prevents...

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