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  1. May 25, 2021 · Longer life expectancies and reduced mortality rates in the United States (U.S.) have led to significant population aging, reduced quality of life and increased mortality from cognitive decline. 1 The onset of MCI and dementia emerge from cognitive decline processes that are complex and dynamic, with a large amount of within-individual and ...

    • Yun Zhang, Ginny Natale, Sean Clouston
    • Jan-Dec 2021
    • 10.1177/15333175211012235
  2. Apr 30, 2024 · With the recent advent of biomarkers that detect the brain changes believed to characterize Alzheimer's disease, it may now be possible to determine which individuals diagnosed with MCI have MCI due to Alzheimer's disease.

  3. Mar 8, 2014 · The construct of mild cognitive impairment (MCI) has evolved over the past 10 years since the publication of the new MCI definition at the Key Symposium in 2003, but the core criteria have remained unchanged.

    • Ronald C. Petersen, Barbara Caracciolo, Barbara Caracciolo, Carol Brayne, Serge Gauthier, Vesna Jeli...
    • 2014
  4. The goal of this article is to broadly cover the state of the current science on MCI, including its phenomenology and neurobiology, how MCI is screened for and assessed, and interventions designed to improve cognitive functioning in MCI, thereby delaying progression to dementia.

    • Nicole D Anderson
    • 2019
  5. Over the years, MCI diagnostic criteria have undergone major changes that correspond to advancements in research. Despite these advancements, current diagnostic criteria for MCI contain issues that are reflected in the research literature.

    • Adam Gerstenecker, Benjamin Mast
    • 2015
  6. May 17, 2022 · Only 18% of Americans are familiar with Mild Cognitive Impairment. Age is the biggest risk factor for MCI. The prevalence of MCI is about 7% at age 60-64 and increases to 25% by age 80-84. Studies estimate that 10-15% of individuals with MCI progress to a diagnosis of dementia each year.

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  8. Jan 11, 2024 · MCI can have several outcomes, with the most important being the progression to dementia. Other cases may revert to normal or remain stable in the MCI stage. A meta-analysis demonstrated that the cumulative incidence of dementia development was 14.9% for MCI patients older than 65 years who were followed for 2 years.

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