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    • No activity against viruses

      • Metronidazole has no activity against viruses (such as those that cause a cold or flu). Do not crush, break, or chew extended-release metronidazole tablets. Swallow them whole.
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  2. Find out how metronidazole treats infections and how to take it. NHS medicines information on metronidazole – what it's used for, side effects, dosage and who can take it.

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  3. Rather than killing a virus directly, antivirals usually suppress the virus's ability to infect and multiply in your cells. These drugs often work by inhibiting molecular interactions and functions needed by the virus to produce new copies of itself.

  4. Mar 16, 2021 · An analysis of the action mechanism of known antiviral drugs concluded that they can increase the cell’s resistance to a virus (interferons), suppress the virus adsorption in the cell or its diffusion into the cell and its deproteinisation process in the cell (amantadine) along with antimetabolites that causes the inhibition of nucleic acids syn...

    • Shamaila Kausar, Fahad Said Khan, Muhammad Ishaq Mujeeb Ur Rehman, Muhammad Akram, Muhammad Riaz, Gh...
    • 2021
  5. Jun 26, 2023 · Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. It is cytotoxic to facultative anaerobic microorganisms.

    • Connor B. Weir, Jacqueline K. Le
    • 2023/06/26
    • What Is Metronidazole?
    • Warnings
    • Before Taking This Medicine
    • How Should I Take Metronidazole?
    • Dosing Information
    • What Should I Avoid While Using Metronidazole?
    • What Are The Side Effects of Metronidazole?
    • What Happens If I Miss A dose?
    • What Happens If I Overdose?
    • What Other Drugs Will Affect Metronidazole?

    Metronidazole is an antibiotic that may be used to treat certain infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream. Metronidazole has been approved to treat: 1. Symptomatic trichomoniasis (a sexually transmitted infection) in adults that has been confirmed by culture or wet smear test 2. Asy...

    To reduce the development of drug-resistant bacteria, do not use metronidazole to treat any condition that has not been checked by your doctor. This medicine will not treat a viral infection such as the common cold or flu. Metronidazole has been shown to be carcinogenic in rats and mice and unnecessary use should be avoided. Do not use metronidazol...

    You should not use this medicine if you are allergic to metronidazole, secnidazole, or tinidazole, or if you: 1. drank alcohol in the past 3 days 2. consumed foods or medicines that contain propylene glycol in the past 3 days or 3. took disulfiram (Antabuse) within the past 14 days 4. have Cockayne Syndrome (a rare genetic disorder that affects gro...

    Take metronidazole exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. 1. The dose depends on the infection being treated. 2. The dosage should be reduced by 50% in those with severe hepatic impairment. 3. In patients undergoing hemodialysis, consider a supplem...

    Trichomoniasis

    Treatment should be individualized. Usual dosages are: 1. One-day treatment: 2 grams as a single oral dose or a split dose given on the same day 2. 7-day course: 250mg three times daily for 7 consecutive days.

    Amebiasis

    1. Adults: acute amebic dysentery. 750mg three times daily for 5 to 10 days. 2. Adults: amebic liver abscess. 500mg or 750mg three times daily for 5 to 10 days. 3. Children: 35mg/kg/24 hours to 50mg/kg/24 hours divided into three doses daily for 10 days. Do not exceed adult dosages.

    Anaerobic Bacterial Infections

    For more serious anaerobic infections, intravenous metronidazole is usually administered initially. 1. Adults: 7.5 mg/kg every 6 hours (this works out at approximately 500mg for a 70kg adult) orally for 7 to 10 days. Maximum dose 4g/24 hours. A longer course of treatment may be required for bone, joint, lower respiratory tract, and endocardium infections.

    Do not drink alcohol or consume foods, medicines, or other products that contain alcohol or propylene glycol while taking metronidazole and for 3 days after your last dose. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin.

    Get emergency medical help if you have signs of an allergic reaction to metronidazole (hives, itching, warmth, or tingling; fever, joint pain; dry mouth, dry vagina; stuffy nose, difficulty breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and ...

    Take the medicine as soon as you can but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, numbness, tingling, or problems with balance or muscle movement.

    Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective. Tell your doctor about all your current medicines. Many drugs can affect metronidazole, especially: 1. antidepressants, such as escitalopram 2. albu...

    • Senior Editorial Pharmacist
  6. Jul 13, 2023 · Metronidazole has no activity against viruses (such as those that cause a cold or flu). Do not crush, break, or chew extended-release metronidazole tablets. Swallow them whole.

  7. Dec 20, 2020 · Q. Do antibiotics work on viruses and bacteria? A: Antibiotics only work for bacterial infections. They work by destroying the bacteria or keeping them from growing out of control. The right antibiotic will do this with little to no harm to the body. Q. How do antiviral drugs differ from antibiotics? A: Antiviral medications don’t destroy the ...

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