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Nov 10, 2022 · Methylprednisolone can help with COVID according to a 2022 systematic review of 33 studies that reported the use of methylprednisolone was associated with: Fewer deaths in the short-term (relative risk [RR] 0.73 which means patients given methylprednisolone were 0.73 times less likely to die within 28 days than those not given methylprednisolone)
May 29, 2020 · A previous study suggested that cytokine release syndrome could be involved in the pathophysiology of severe or critical COVID-19 cases and frequently results in death. 2 Hence, early recognition and effective suppression of the cytokine storm may be life-saving in severe or critical patients.
- Jing Liu, Xiaobin Zheng, Yiying Huang, Hong Shan, Jin Huang
- 10.1016/j.jaci.2020.05.021
- 2020
- 2020/08
Mar 30, 2022 · The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the...
Jun 17, 2021 · There are limited antiviral options for the treatment of patients with COVID-19. Ivermectin (IVM), a macrocyclic lactone with a wide anti-parasitary spectrum, has shown potent activity against SARS-CoV-2 in vitro.
- Alejandro Krolewiecki, Adrián Lifschitz, Matías Moragas, Marina Travacio, Ricardo Valentini, Daniel ...
- 2021
May 3, 2023 · At the time of writing, it states that systemic corticosteroids (particularly dexamethasone), interleukin-6 receptor antagonists (such as tocilizumab), and Janus kinase inhibitors (such as baricitinib) reduce mortality and have other benefits in patients with severe covid-19, such as reducing the length of hospital stay and the time needed on a ...
Oct 24, 2023 · Paxlovid is the first FDA-approved oral antiviral drug against COVID-19 . It is a combination of nirmatrelvir, which inhibits the main protease (Mpro) of SARS-CoV-2, and ritonavir, the inhibitor of cytochrome P450-3A4, thus slowing down nirmatrelvir metabolism.
Jan 26, 2022 · Investigators assessed the in vitro activities of seven monoclonal antibodies and three antiviral drugs against Covid-19 variants of concern. All the antibodies showed either no or weak...
