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- The vast assortment of dog breed shapes has been created by strong and continuous artificial selection, leading to the fixation of extreme phenotypes within hundreds of distinct closed breeding populations. The resulting population structure has become a powerful tool for defining chromosomal regions underlying skeletal variation.
www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/dog-breed
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Why are dog breeds important?
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Oct 2, 2019 · Genetic and phenotypic variation across dog breeds provides a unique opportunity for investigating questions about the evolution and biological basis of complex traits.
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Second, if breed differences in behaviour are highly...
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Sep 25, 2017 · Cancer is an extremely common disease in dogs, and findings from breed-specific studies reveal information that is relevant for basic cancer biology. Abstract. The domestic dog represents...
- Elaine A. Ostrander, Robert K. Wayne, Adam H. Freedman, Brian W. Davis, Brian W. Davis
- 2017
Jan 30, 2023 · In this study we have applied the composite index method, CSS, to evaluate genomic regions that differentiate dogs from three breed groups. The CSS method has been shown to be a sensitive...
Mar 9, 2010 · Today, the 400 plus breeds of dogs vary in size, shape of the skull and modifications of the postcranial skeleton (in particular the limb bones) to a degree that would suggest species-level, if not generic-level, differences, if their remains were discovered in the wild.
- Rodney L Honeycutt
- rodney.honeycutt@pepperdine.edu
- 2010
Jul 29, 2020 · Our previous work demonstrated that genetic relatedness among breeds accounts for a substantial portion of variation in dog cognition. Here, we investigated the genetic architecture of breed differences in cognition, seeking to identify genes that contribute to variation in cognitive phenotypes.
- Gitanjali E Gnanadesikan, Brian Hare, Noah Snyder-Mackler, Josep Call, Juliane Kaminski, Ádám Miklós...
- 10.1093/icb/icaa112
- 2020
- Integr Comp Biol. 2020 Oct; 60(4): 976-990.
Aug 15, 2023 · We report the analysis of > 48 M single-nucleotide, indel, and structural variants spanning the autosomes, X chromosome, and mitochondria. We discover more than 75% of variation for 239 sampled breeds. Allele sharing analysis indicates that 94.9% of breeds form monophyletic clusters and 25 major clades.
Apr 25, 2017 · A new family tree of dogs containing more than 160 breeds reveals the hidden history of man’s best friend, and even shows how studying canine genomes might help with research into human disease...
